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This combination contains a centrally acting cough suppressant and menthol to soothe upper-airway irritation. The selected syrup relieves dry, non-productive coughs associated with colds and bronchitis.
This combination contains a cough suppressant, pain and fever reliever, and sedating antihistamine. It relieves night-time cold and flu symptoms including a dry tickly cough, runny nose and aches.
This oral liquid combines a cough suppressant, nasal decongestant and sedating antihistamine. It is licensed when dry cough, nasal congestion and histamine-related symptoms occur together.
Dextrose monohydrate is a hydrated form of glucose, the body’s main energy-supplying carbohydrate. The selected product is an intravenous glucose solution licensed to provide energy or carry compatible medicines.
Diamorphine hydrochloride is a strong opioid rapidly converted to active opioid metabolites, including morphine. The selected injection is licensed for severe pain associated with surgery, myocardial infarction or terminal illness, and breathlessness caused by acute pulmonary oedema.
Diazepam is a prescription benzodiazepine that reduces excessive activity in the brain and nervous system. It is used for severe anxiety, seizures, muscle spasm, alcohol withdrawal and sedation around procedures. Continued use requires review because it can cause sedation, dependence and withdrawal.
Diazoxide raises blood glucose by reducing insulin release from the pancreas. The selected UK oral product is licensed for severe, persistent hypoglycaemia that cannot be managed by surgery or another specific treatment.
Dibrompropamidine isetionate is a topical antiseptic with activity against certain bacteria and fungi. The selected UK cream is licensed for nappy rash, minor skin injuries, susceptible surface infections, some superficial fungal infections and otitis externa.
Diclofenac diethylamine is a topical non-steroidal anti-inflammatory drug (NSAID) applied to the skin to reduce local pain and inflammation after sprains, strains and bruises.
Diclofenac diethylammonium is a topical non-steroidal anti-inflammatory drug (NSAID) applied to the skin to reduce local pain and inflammation affecting joints, muscles and nearby soft tissues.
Diclofenac potassium is a non-steroidal anti-inflammatory drug (NSAID) that reduces pain and inflammation. This immediate-release tablet is licensed for short-term treatment of acute painful or inflammatory conditions.
Diclofenac sodium is a non-steroidal anti-inflammatory drug (NSAID) that reduces pain and inflammation. Systemic forms treat inflammatory joint disorders and painful musculoskeletal, traumatic and postoperative conditions; gel targets local muscle and injury pain.
This prescription-only combination contains diclofenac, an anti-inflammatory painkiller, and misoprostol, which helps protect the stomach and duodenum. It is used for osteoarthritis or rheumatoid arthritis when an adult needs diclofenac and particular protection against NSAID-related ulcers.
Dicycloverine hydrochloride is an antispasmodic that relaxes smooth muscle in the stomach and intestines. It relieves cramps, pain and discomfort caused by functional gastrointestinal spasm, including irritable bowel symptoms.
Dienogest is a progestogen that reduces hormonal stimulation of endometriosis tissue. The selected UK product is licensed to treat endometriosis and can help reduce symptoms such as pelvic pain.
A combined hormonal contraceptive containing a progestogen and an oestrogen. It is licensed to prevent pregnancy and treat heavy menstrual bleeding without an underlying womb disorder when oral contraception is also wanted.
Diethylamine salicylate is a topical salicylate pain reliever supplied as a cream. It relieves rheumatic and minor musculoskeletal pain, including strains, bruises, backache and exercise-related stiffness.
Diethylstilbestrol is a synthetic non-steroidal oestrogen used for castration-resistant prostate cancer when alternatives are unsuitable. Serious risks, particularly blood clots, require specialist supervision.
Difelikefalin acetate is a selective kappa-opioid receptor agonist that acts mainly outside the brain. It reduces moderate-to-severe itching associated with chronic kidney disease in adults receiving haemodialysis.
Digoxin slows electrical conduction through the heart and increases the strength of contraction. It is used for certain supraventricular arrhythmias and selected people with systolic heart failure.
Dihydrocodeine tartrate is an opioid analgesic that changes how the brain perceives pain. The selected prolonged-release product is licensed for severe pain associated with cancer and other chronic conditions.
This combines paracetamol with the opioid dihydrocodeine. The selected Paramol product is licensed for acute moderate pain not relieved by paracetamol, ibuprofen or aspirin alone.
Diltiazem hydrochloride is a rate-limiting calcium-channel blocker used mainly for high blood pressure and angina. It relaxes blood vessels, reduces cardiac workload and can slow heart rate and conduction.
Dimethyl fumarate is an oral immunomodulator. Selected gastro-resistant capsules are licensed for relapsing-remitting multiple sclerosis, while Skilarence gastro-resistant tablets are licensed for moderate to severe plaque psoriasis requiring systemic treatment.
Dimeticone is a silicone-based topical treatment for confirmed head-lice infestation. It coats lice and disrupts their water balance rather than poisoning their nervous system.
Dinoprostone is a manufactured form of prostaglandin E2, a hormone-like substance involved in preparing the cervix and stimulating uterine contractions. Selected vaginal and intravenous formulations are used by specialist maternity teams to induce labour.
Dinutuximab beta is a monoclonal antibody used as specialist immunotherapy for neuroblastoma. It targets GD2 and helps the immune system attack cancer cells. Its licensed role includes certain high-risk, relapsed or refractory disease in patients aged 12 months and over.
Diphenhydramine hydrochloride is a sedating antihistamine with antimuscarinic effects. Selected oral tablets are licensed for temporary sleep disturbance, while the cream relieves local allergic itching, rashes, hives, stings and insect bites.
This oral syrup combines a sedating antihistamine and cough suppressant, an expectorant and menthol. It relieves dry or chesty cough, associated congestion and related sleep disturbance.
This combination contains paracetamol for pain relief and diphenhydramine, a sedating antihistamine. It is licensed for short-term relief of bedtime pain that is making sleep difficult, not sleeplessness without pain.
This combination relieves cold and flu symptoms. Daytime tablets contain paracetamol for pain and fever with pseudoephedrine for nasal congestion. Night-time tablets contain paracetamol with sedating diphenhydramine.
An inactivated combination vaccine that prompts immunity against diphtheria, tetanus and pertussis. It is used after primary immunisation and during pregnancy to help protect newborns against pertussis.
This inactivated combined vaccine helps protect against diphtheria, tetanus and polio. Revaxis is a booster after primary vaccination and is not intended to start primary immunisation.
A combined, non-live vaccine that helps the immune system recognise diphtheria, tetanus, pertussis and poliovirus. Selected UK products are licensed as boosters and during pregnancy to help protect young infants against pertussis.
A non-live combination vaccine that stimulates protection against diphtheria, tetanus, whooping cough, polio and Haemophilus influenzae type b (Hib). This product is licensed for childhood primary and booster immunisation. Routine NHS infant vaccination uses a six-in-one vaccine that also covers hepatitis B.
A combined, non-live vaccine that stimulates protection against diphtheria, tetanus, whooping cough, polio, hepatitis B and invasive disease caused by Hib. It is used in the UK routine childhood immunisation programme and for eligible catch-up vaccination.
Dipyridamole is an antiplatelet treatment that makes platelets less likely to form unwanted clots. Selected UK products are licensed to help prevent further ischaemic stroke or transient ischaemic attack, or to support anticoagulation in people with prosthetic heart valves.
Diroximel fumarate is an oral disease-modifying treatment for adults with relapsing-remitting multiple sclerosis. It reduces inflammatory disease activity but does not cure MS.
Disodium clodronate is a non-amino bisphosphonate that slows bone breakdown. The selected product manages bone damage, bone pain and raised blood calcium associated with breast cancer or multiple myeloma.
This oral rehydration salt preparation contains glucose and electrolytes. Mixed correctly with water, it replaces fluid and salts lost through watery diarrhoea but does not treat the underlying cause.
Disodium levofolinate supplies the biologically active form of folinic acid. It protects healthy cells from folate-antagonist toxicity, particularly with methotrexate, and strengthens fluorouracil's anticancer effect.
A rectal saline laxative and bowel cleanser. It draws water into the bowel, softening its contents and stimulating evacuation for constipation or bowel clearance around certain procedures, operations and obstetric care.
Disopyramide is a prescription antiarrhythmic that alters electrical conduction in the heart. It treats or prevents selected abnormal heart rhythms and can help maintain normal rhythm after cardioversion.
Disopyramide phosphate is a class Ia antiarrhythmic used under specialist supervision to prevent or control selected abnormal heart rhythms.
Disulfiram supports alcohol abstinence alongside psychological and social support. It does not treat withdrawal or directly reduce cravings; it deters drinking by causing a potentially dangerous reaction with alcohol.
A synthetic form of the fat-soluble vitamin E. The selected oral suspension is licensed to correct vitamin E deficiency caused by impaired absorption and acts as an antioxidant in lipid-rich cell membranes.
Dobutamine hydrochloride is an intravenous sympathomimetic that strengthens heart contractions and can increase cardiac output. It is used under close hospital supervision for short-term circulatory support and certain cardiac stress echocardiograms.
Docetaxel is a taxane chemotherapy that disrupts cancer-cell division. It is used alone or with other treatments for several breast, lung, prostate, gastric and head-and-neck cancers.
Docetaxel is a taxane chemotherapy that disrupts cancer-cell division. It may be used alone or with other anticancer treatments for several solid tumours.
Dolutegravir sodium is an antiretroviral that blocks HIV integrase. Used with other antiretrovirals, it controls but does not cure HIV infection.
This fixed combination contains two antiretrovirals that act at different stages of HIV replication. It controls HIV-1 in suitable adults and adolescents but does not cure it.
A fixed combination of two antiretroviral treatments that block HIV-1 replication at different stages. It replaces stable treatment in selected adults whose virus is already suppressed and who meet treatment-history and resistance criteria.
Domperidone is a prescription-only dopamine antagonist used to relieve nausea and vomiting in eligible adults and adolescents.
Domperidone maleate is a prescription-only anti-sickness treatment and peripheral dopamine antagonist. The selected product is licensed to relieve nausea and vomiting.
Donanemab is a monoclonal antibody for mild cognitive impairment or mild dementia caused by Alzheimer’s disease. It can slow clinical decline but does not reverse or cure the disease. UK use is limited to adults with confirmed amyloid pathology and no more than one ApoE4 gene copy.
Donepezil hydrochloride is an acetylcholinesterase inhibitor used to treat symptoms of Alzheimer’s dementia. It may support memory, thinking and everyday functioning, but does not cure Alzheimer’s disease or stop the underlying disease process.
Dopamine hydrochloride is a short-acting catecholamine that supports the heart and circulation. It is usually given in hospital for serious hypotension, shock, poor tissue perfusion or low cardiac output.
Doravirine is a non-nucleoside reverse transcriptase inhibitor (NNRTI) used with other antiretrovirals to control HIV-1 when there is no evidence of NNRTI resistance.
A fixed-combination antiretroviral treatment containing one NNRTI and two nucleoside/nucleotide reverse transcriptase inhibitors. It is used for suitable people with HIV-1 whose virus is not resistant to its components.
Dornase alfa is an inhaled recombinant human enzyme that breaks down DNA in thick cystic fibrosis mucus, making airway secretions less sticky and helping lung function.