dextromethorphan hydrobromide + paracetamol + promethazine at a glance
Medicine classes
Antitussive, analgesic–antipyretic and sedating antihistamine.
Drowsiness
Promethazine commonly causes sleepiness and may impair concentration, vision and coordination.
What is dextromethorphan hydrobromide + paracetamol + promethazine used for?
These products relieve symptoms rather than treating the underlying viral infection.
Cold, chills and influenza symptoms at night
Headache, sore-throat pain, shivering, feverish discomfort and aches
Dry, irritating or tickly cough
Runny nose
How does dextromethorphan hydrobromide + paracetamol + promethazine work?
Dextromethorphan reduces the cough reflex. Paracetamol reduces pain and fever. Promethazine blocks histamine and has anticholinergic and sedating effects, reducing a runny nose but also causing drowsiness and dry mouth.
How to take dextromethorphan hydrobromide + paracetamol + promethazine
Use by mouth according to the specific product instructions. Shake oral solution before use and measure it only with the supplied cup. Avoid alcohol, and do not drive or operate machinery if sleepy, dizzy, visually affected or unable to concentrate.
Check other products for paracetamol, antihistamines and cold or cough ingredients.
The oral solution contains ethanol, propylene glycol and maltitol.
Capsules contain lactose.
dextromethorphan hydrobromide + paracetamol + promethazine side effects
Common or expected effects
- Drowsiness or reduced alertness
- Dizziness or headache
- Dry mouth
- Blurred vision
- Impaired attention or coordination
- Nausea, vomiting or abdominal discomfort
Get urgent medical advice
- Severe allergic reaction
- Blistering, peeling or widespread severe skin reaction
- Serotonin syndrome
- Severe confusion, hallucinations, seizure or respiratory depression
- Irregular heartbeat or fainting
- Jaundice or other signs of liver dysfunction
- Difficulty passing urine
dextromethorphan hydrobromide + paracetamol + promethazine in pregnancy
Do not use during pregnancy without medical advice. Evidence for the complete combination and dextromethorphan is limited. The oral solution’s ethanol and propylene glycol also require consideration.
dextromethorphan hydrobromide + paracetamol + promethazine while breastfeeding
Seek advice before use while breastfeeding. Promethazine can cause infant drowsiness or poor feeding and may affect milk production; information about dextromethorphan exposure is limited. If advised to use it, monitor for unusual sleepiness, irritability, poor feeding or inadequate weight gain, and avoid bed-sharing after taking a sedating medicine.
dextromethorphan hydrobromide + paracetamol + promethazine interactions
Ask a pharmacist or prescriber to check all prescription, non-prescription and herbal products.
Monoamine oxidase inhibitors
Concurrent or recent use is contraindicated because severe reactions, including serotonin syndrome, can occur.
SSRIs and other serotonergic antidepressants
Dextromethorphan can increase serotonin-syndrome risk. Product restrictions differ, so obtain professional advice.
Common questions about dextromethorphan hydrobromide + paracetamol + promethazine
Answers are fully visible for fast scanning and source review.
Will it make me sleepy?
It commonly can. Promethazine is sedating, and dextromethorphan may add dizziness or drowsiness.
Can I drink alcohol with it?
Sources
These sources were used to prepare and review this medicine page.
Prepared and reviewed by the iatroX editorial team.