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A human plasma-derived prothrombin complex concentrate containing clotting factors II, VII, IX and X, plus proteins C and S. It temporarily replaces deficient vitamin K-dependent factors when rapid correction is needed.
Factor IX replaces the clotting protein missing or reduced in haemophilia B, helping the body form stable clots and temporarily reducing bleeding.
Factor VIII is a blood-clotting protein that is reduced or absent in haemophilia A. Replacement factor VIII helps prevent or control bleeding.
This treatment contains human factor VIII and von Willebrand factor, proteins that help form stable blood clots. It replaces deficient factors in von Willebrand disease and haemophilia A to prevent or control bleeding.
A human plasma-derived clotting-factor mixture that promotes clotting without relying on factor VIII. It is usually used to control or prevent bleeding when inhibitors make replacement clotting factors ineffective.
Factor XIII is a human plasma-derived clotting-factor replacement for inherited factor XIII deficiency, which can cause bleeding and impaired wound healing.
Famciclovir is a prescription antiviral converted in the body to penciclovir. In adults, it is used for shingles, including around the eye, and for treating or suppressing genital herpes.
Famotidine is a histamine H2-receptor antagonist that reduces stomach-acid production. In the UK, the selected tablets are licensed for certain stomach and duodenal ulcers, reflux oesophagitis and Zollinger–Ellison syndrome.
Fampridine is a potassium-channel blocker used to improve walking in some adults with multiple sclerosis and walking disability. It treats a symptom rather than changing the underlying disease.
Faricimab is a bispecific antibody injected into the eye by a trained healthcare professional. It treats certain retinal conditions in adults by reducing abnormal blood-vessel leakage, swelling and growth.
Febuxostat is a xanthine oxidase inhibitor that reduces uric acid production. It is used in adults with chronic high urate levels where crystal deposition has caused gouty arthritis or tophi.
Febuxostat hemihydrate is a xanthine oxidase inhibitor that lowers uric acid production. It is used in adults for chronic hyperuricaemia where urate deposits have formed. The selected product is also licensed for high uric acid associated with certain blood-cancer chemotherapy.
Febuxostat magnesium provides febuxostat, a selective xanthine oxidase inhibitor that lowers uric acid. It is used to manage gout where urate deposits have formed.
Fedratinib is an oral targeted anticancer treatment that inhibits JAK2 signalling. It reduces disease-related spleen enlargement or symptoms in adults with certain forms of myelofibrosis, including after ruxolitinib treatment.
Felodipine is a dihydropyridine calcium-channel blocker that relaxes arteries. Selected UK prolonged-release products are licensed for high blood pressure and chronic stable angina.
Fenfluramine hydrochloride is an antiseizure treatment affecting serotonin signalling and the sigma-1 receptor. In the UK, it is used with other antiseizure treatments for seizures associated with Dravet syndrome or Lennox–Gastaut syndrome in people aged 2 years and over.
Fenofibrate is a fibrate that lowers triglycerides and can improve other blood-fat levels. It is generally used with diet and lifestyle measures when triglycerides are severely raised, or for selected mixed lipid disorders when statins are unsuitable or insufficient.
Fentanyl is a strong opioid painkiller that changes how the brain and nervous system respond to pain. The selected skin patches provide continuous treatment for severe, persistent pain in people already established on opioid therapy.
Fentanyl citrate provides fentanyl, a potent opioid analgesic. Selected products include hospital injections for surgical analgesia or severe pain, and rapid-acting sublingual or nasal formulations for breakthrough cancer pain in adults already taking regular opioid therapy.
Ferric derisomaltose is an intravenous iron complex that replenishes iron needed to make haemoglobin and healthy red blood cells. Diafer is licensed for adults with chronic kidney disease on dialysis when oral iron is ineffective or cannot be used.
Ferric maltol is an oral iron preparation used to restore low iron stores. Iron is needed to make haemoglobin; deficiency can cause anaemia, tiredness and breathlessness.
Ferrous fumarate is an oral iron medicine used to prevent or treat iron deficiency anaemia. It supplies iron needed to make haemoglobin and healthy red blood cells.
This combination provides iron for haemoglobin and folic acid for normal blood-cell formation. The selected product is licensed during the second and third trimesters of pregnancy to prevent iron deficiency and megaloblastic anaemia; it does not treat established megaloblastic anaemia.
Ferrous sulfate is an oral iron medicine used to make healthy red blood cells. Selected UK tablets and drops treat iron-deficiency anaemia; Ironorm Drops are also licensed for prevention.
Fesoterodine fumarate is a prescription antimuscarinic used in adults with overactive bladder syndrome. It helps reduce urinary urgency, frequent urination and leakage caused by urgency.
Feverfew is a herbal product made from Tanacetum parthenium. Selected UK products are traditionally used to help prevent migraine headaches. Registration is based on longstanding use, not demonstrated clinical effectiveness.
Fexofenadine hydrochloride is a less-sedating H1 antihistamine that blocks histamine to reduce allergic symptoms. The selected UK product relieves itching, swelling and rash associated with chronic idiopathic urticaria in adults and adolescents aged 12 years and over.
Fezolinetant is a non-hormonal treatment for moderate to severe hot flushes and night sweats associated with menopause. It acts on the brain’s temperature-control system rather than replacing oestrogen.
Fidaxomicin is a macrocyclic antibiotic that acts mainly inside the bowel. It treats Clostridioides difficile infection, which can cause diarrhoea and inflammation of the large bowel.
Filgotinib maleate is an oral, targeted anti-inflammatory treatment that preferentially inhibits Janus kinase 1 (JAK1). In adults, it is licensed for certain cases of active rheumatoid arthritis and ulcerative colitis when previous treatments were inadequate or not tolerated.
Filgrastim is a granulocyte-colony stimulating factor that helps bone marrow make and release neutrophils, a type of white blood cell. It is mainly used to manage neutropenia and mobilise blood-forming stem cells for collection.
Finasteride is a prescription-only 5-alpha-reductase inhibitor. In the UK, selected tablets are licensed for male pattern hair loss in men or benign prostate enlargement, depending on the formulation.
Finerenone is a non-steroidal, selective mineralocorticoid receptor antagonist. The selected UK product is licensed for adults with symptomatic chronic heart failure and a left ventricular ejection fraction of 40% or higher.
Fingolimod hydrochloride is a prescription disease-modifying treatment for highly active relapsing-remitting multiple sclerosis. It reduces inflammatory immune-cell movement into the brain and spinal cord, helping reduce relapses and disability progression; it does not cure multiple sclerosis.
Flavoxate hydrochloride is a urinary antispasmodic that relaxes urinary-tract smooth muscle. It provides symptomatic relief from bladder and urinary-tract spasm, discomfort and urgency.
Flecainide acetate is a class IC anti-arrhythmic that slows electrical conduction through the heart. Specialists use it for selected serious atrial, ventricular and accessory-pathway rhythm disorders.
Flucloxacillin sodium is a prescription penicillin antibiotic that kills susceptible bacteria. It is mainly used for susceptible staphylococcal and streptococcal infections, particularly of the skin, wounds and bones, and some respiratory or ear infections. Injectable forms are generally used in hospital when oral treatment is unsuitable or for certain serious infections.
Fluconazole is a triazole antifungal used for susceptible yeast and fungal infections, including thrush, invasive candidiasis and cryptococcal meningitis. It can also prevent infection in selected high-risk people.
Fludarabine phosphate is a cytotoxic purine analogue that interferes with cancer-cell growth. The selected oral product is licensed for adults with B-cell chronic lymphocytic leukaemia who have sufficient bone-marrow reserve.
Fludrocortisone acetate is a corticosteroid with strong mineralocorticoid activity. It replaces mineralocorticoid hormone, helping the kidneys retain sodium and water and excrete potassium.
Fludroxycortide is a potent corticosteroid applied to the skin to reduce inflammation, itching and irritation. It is available as a cream and an occlusive tape.
Flumazenil is an antidote that reverses some or all central sedative effects of benzodiazepines. It is usually given in hospital after sedation or, in selected cases, for intoxication caused only or mainly by benzodiazepines.
Fluocinolone acetonide is a corticosteroid that reduces inflammation. Skin preparations treat inflammatory, itchy or allergic disorders, while an intravitreal implant treats selected chronic inflammatory or swelling-related eye conditions.
Fluocinonide is a potent corticosteroid applied to the skin to reduce inflammation and itching in selected skin conditions.
Fluorescein sodium is a temporary fluorescent diagnostic dye, not a treatment. Injection makes retinal and choroidal blood vessels visible during eye photography; eye drops highlight surface damage and support pressure measurement and hard contact-lens fitting.
These eye drops combine lidocaine, which temporarily numbs the eye surface, with fluorescein, a dye that highlights surface changes. Their licensed role is to support eye-pressure measurement using Goldmann tonometry.
Fluorometholone is a corticosteroid eye drop that reduces inflammation at the front of the eye. The selected UK product is licensed for steroid-responsive inflammation affecting the conjunctiva, cornea and other anterior eye structures.
Fluorouracil disrupts DNA and RNA production. Injections are used for cancer treatment, particularly bowel and breast cancers, while cream treats defined areas of sun-damaged actinic keratosis.
This prescription skin solution combines fluorouracil, which limits abnormal cell growth, with salicylic acid, which removes thickened surface skin and improves penetration. It is licensed for mildly or moderately thick actinic keratoses in immunocompetent adults.
Fluoxetine hydrochloride is a prescription selective serotonin reuptake inhibitor (SSRI) antidepressant. It is mainly used for depression, obsessive-compulsive disorder and, with psychotherapy, bulimia nervosa.
Flupentixol decanoate is a long-acting, first-generation antipsychotic supplied as an oily depot injection. The selected UK product is licensed for schizophrenia and other psychoses in people stabilised on oral therapy.
Flupentixol dihydrochloride is the oral salt of flupentixol, a thioxanthene with antipsychotic pharmacology. The selected UK tablets are licensed for symptomatic treatment of depression, with or without anxiety.
Flurazepam monohydrochloride is a long-acting benzodiazepine that strengthens calming GABA signalling in the brain. It is licensed for severe insomnia, including difficulty falling asleep or frequent night-time waking.
Flurbiprofen is a non-steroidal anti-inflammatory drug (NSAID) that reduces pain and inflammation. Tablets are licensed for painful inflammatory conditions; lozenges and oromucosal spray relieve sore-throat symptoms.
Flutamide is a non-steroidal antiandrogen used for advanced prostate cancer, usually alongside treatment that reduces testosterone or after surgical castration.
Fluticasone furoate is a corticosteroid nasal spray used to relieve allergic rhinitis symptoms, including congestion, sneezing, itching and a runny nose.
A dry-powder inhaler combining an inhaled corticosteroid with two long-acting bronchodilators. It is licensed for maintenance treatment of inadequately controlled moderate to severe COPD in adults. It is not a rescue inhaler or licensed for asthma.
Fomepizole blocks the conversion of ethylene glycol into more harmful chemicals. The selected UK product is licensed for confirmed or suspected ethylene glycol poisoning and is given in hospital. Specialist use for methanol poisoning is established but not licensed for this product.
Formoterol is an inhaled long-acting beta2 agonist that relaxes airway muscle and makes breathing easier. The selected product is used alongside inhaled corticosteroids for asthma and to relieve symptoms in adults with chronic obstructive pulmonary disease (COPD).
Futibatinib is a targeted cancer treatment that irreversibly blocks fibroblast growth factor receptors (FGFRs). In the UK, it is used alone for selected adults with advanced bile duct cancer whose tumour has an FGFR2 fusion or rearrangement and has progressed after previous systemic treatment.