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Aclidinium bromide and formoterol combine two long-acting bronchodilators in one inhaler. It is used as regular maintenance treatment to relieve symptoms in adults with chronic obstructive pulmonary disease (COPD); it is not a reliever for sudden breathing attacks.
This combines acrivastine, an antihistamine, with pseudoephedrine, a decongestant. It provides symptomatic relief of allergic rhinitis when allergy symptoms occur with nasal or sinus congestion.
Activated dimeticone, also called simeticone, is a non-absorbed antiflatulent that helps gas bubbles combine and pass more easily. The selected product is licensed for wind and griping pain caused by swallowed air in infants, although evidence of benefit for infant colic is limited.
Adalimumab is a biological monoclonal antibody that reduces inflammation by blocking tumour necrosis factor alpha (TNF-alpha). Specialists use it for inflammatory joint, skin, bowel and eye conditions.
Adapalene is a topical retinoid used for acne. It helps prevent blocked pores and reduces inflammatory spots, with little absorption through the skin.
A prescription gel combining a topical retinoid with an antimicrobial and peeling agent for acne with blocked pores and inflamed spots.
Adenosine is a naturally occurring nucleoside that briefly affects electrical conduction and blood flow in the heart. In hospital, it is used to restore certain rapid rhythms, help identify an arrhythmia, or increase coronary blood flow during myocardial perfusion imaging.
Adrenaline, also called epinephrine, stimulates alpha and beta adrenergic receptors. The selected products provide emergency first aid for anaphylaxis while urgent medical help is obtained.
Adrenaline acid tartrate provides adrenaline by injection for emergency treatment of anaphylaxis and other acute, severe allergic reactions. It supports blood pressure, opens airways and reduces swelling.
This injection combines bupivacaine, a long-acting local anaesthetic, with adrenaline, which narrows nearby blood vessels and helps the anaesthetic remain at the injection site. It is used by trained clinicians to numb an area for surgery or to manage acute pain.
This injection combines lidocaine, a local anaesthetic, with adrenaline, which reduces local blood flow and slows lidocaine absorption. It is used by trained healthcare professionals to numb a region of the body for procedures.
Adrenaline tartrate supplies adrenaline, which rapidly counters dangerous airway, breathing and circulation effects of anaphylaxis. Jext is a single-use auto-injector for emergency treatment before an ambulance arrives.
An injectable local anaesthetic combining lidocaine, which numbs nerves, with adrenaline, which narrows nearby blood vessels. It is given by trained healthcare professionals for regional anaesthesia during procedures and certain pain-relief blocks.
Afatinib dimaleate is a targeted anticancer treatment called a protein kinase inhibitor. It is used on its own for certain locally advanced or metastatic non-small cell lung cancers, including some with activating EGFR mutations.
Aflibercept is a biological protein that blocks signals involved in abnormal blood-vessel growth and leakage. Selected products are used as specialist injections into the eye for retinal conditions or, in a different formulation, as an intravenous cancer treatment with chemotherapy.
Agalsidase alfa is a laboratory-made form of the human enzyme alpha-galactosidase A. It is used as enzyme replacement therapy for people with confirmed Fabry disease, helping break down material that accumulates when this enzyme is deficient.
Agalsidase beta is a recombinant form of human alpha-galactosidase A used as enzyme replacement therapy. It helps clear substances that accumulate inside cells in Fabry disease and is given under specialist supervision by intravenous infusion.
Agnus castus is a herbal product made from the fruit of Vitex agnus-castus. The selected UK product is traditionally used to relieve premenstrual symptoms, but its registration is based on longstanding use rather than proven clinical effectiveness.
Agomelatine is an antidepressant licensed to treat major depressive episodes in adults. It acts on melatonin and serotonin receptors and requires liver-function monitoring because it can sometimes cause liver injury.
A sterile solution containing 18 amino acids used as part of parenteral nutrition when nutrition by mouth or through the gut is impossible, inadequate or contraindicated.
A three-chamber parenteral nutrition emulsion containing amino acids, glucose and fats. It supplies energy, protein building blocks, essential fatty acids and fluid when nutrition by mouth or through the gut is impossible, inadequate or contraindicated.
An intravenous amino-acid solution used as the protein component of parenteral nutrition for babies and children when feeding by mouth or through the gut is impossible, inadequate or unsuitable. It is normally combined with energy and other required nutrients.
This is a three-compartment parenteral nutrition infusion containing amino acids, glucose and fats. It provides protein-building material and energy directly into the bloodstream when nutrition by mouth or through the gut is impossible, insufficient or contraindicated.
A parenteral nutrition emulsion containing amino acids, glucose and fats. It supplies protein-building components and energy directly into the bloodstream when nutrition by mouth or through the gut is impossible, insufficient or contraindicated.
This is a three-chamber parenteral nutrition infusion containing amino acids, glucose and lipids, including essential fatty acids. It supplies energy, protein-building components and fluid when oral or tube feeding is impossible, inadequate or contraindicated; electrolytes and micronutrients must be prescribed separately as needed.
This is a two-chamber parenteral nutrition infusion containing amino acids, glucose, electrolytes and fluid. It supports adults and children aged 2 to 17 years with moderate to severe catabolism when nutrition through the mouth or gut is impossible, insufficient or contraindicated. Other nutritional components, including lipid, vitamins and trace elements, may still be required.
This is a parenteral nutrition solution containing amino acids, glucose, electrolytes and fluid. It is infused into the bloodstream when nutrition by mouth or through the gut is impossible, insufficient or contraindicated.
A sterile parenteral nutrition solution containing amino acids, glucose, electrolytes and fluid. It is used when nutrition by mouth or through the gut is impossible, insufficient or contraindicated in people with mild to moderate catabolism. Lipids, essential fatty acids, vitamins and trace elements may need to be supplied separately.
A three-compartment parenteral nutrition preparation containing amino acids, glucose, fats and electrolytes. It supplies nutrition directly into the bloodstream when feeding by mouth or through the gut is impossible, insufficient or unsuitable.
This is a three-part parenteral nutrition emulsion containing amino acids, glucose, fats and electrolytes. It provides nutrition directly into the bloodstream when feeding by mouth or through the gut is impossible, insufficient or unsuitable.
A combined parenteral nutrition product for preterm newborns. It supplies amino acids, glucose, electrolytes and, when needed, fats directly into the bloodstream when milk or other enteral feeding is unsuitable or insufficient.
A three-chamber parenteral nutrition emulsion containing amino acids, glucose, fats, electrolytes and fluid. It provides nutrition directly into the bloodstream when nutrition by mouth or through the gut is impossible, inadequate or unsuitable.
This is a three-chamber intravenous nutrition product containing amino acids, glucose, electrolytes and an optional lipid emulsion. It is used when a child or adolescent cannot receive enough nutrition by mouth or through the gut.
This is a three-chamber parenteral nutrition infusion containing amino acids, glucose, fats, electrolytes and fluid. It supports nutrition when food cannot be taken or absorbed adequately through the gut.
A parenteral nutrition solution containing amino acids, glucose and electrolytes. It provides nutrition directly into the bloodstream when feeding by mouth or through the gut is impossible, inadequate or contraindicated. Lipids, vitamins and trace elements may need to be added according to individual requirements.
This is a glucose-free amino acid and electrolyte solution used inside the abdomen for peritoneal dialysis. It removes fluid and waste across the peritoneal membrane while supplying absorbable amino acids, particularly for people with chronic kidney failure who are malnourished.
This is a three-chamber parenteral nutrition infusion containing amino acids, glucose, fats and electrolytes. It is used in adults who cannot obtain enough nutrition by mouth or through a feeding tube.
This is a sterile intravenous mixture of amino acids, the building blocks used to make proteins. It is used as part of parenteral nutrition when adequate nutrition cannot be absorbed by mouth or through the gut, alongside suitable energy and other required nutrients.
Albutrepenonacog alfa is a recombinant clotting factor IX joined to albumin so it remains active in the circulation for longer. It replaces missing factor IX to prevent or control bleeding in people with haemophilia B.
Alclometasone dipropionate is a moderately potent corticosteroid applied to the skin. It reduces inflammation and itching in corticosteroid-responsive skin conditions such as eczema and dermatitis.
Alectinib hydrochloride is a targeted cancer treatment called an ALK tyrosine kinase inhibitor. It is used for adults with ALK-positive non-small-cell lung cancer, including after complete tumour removal and in advanced disease.
Alemtuzumab is a monoclonal antibody that targets CD52-bearing lymphocytes. It is licensed for defined adults with highly active relapsing-remitting multiple sclerosis and is given under specialist hospital supervision.
Alendronate sodium trihydrate provides alendronic acid, a bisphosphonate that slows bone breakdown. Selected products are licensed to treat postmenopausal osteoporosis and reduce spine and hip fracture risk.
This prescription tablet combines alendronate, which slows bone breakdown, with colecalciferol (vitamin D3), which supports calcium absorption and normal bone formation. It is licensed for postmenopausal osteoporosis in women at risk of vitamin D insufficiency and reduces vertebral and hip fracture risk.
Alfacalcidol is a vitamin D analogue that the liver rapidly converts into active vitamin D. It helps regulate calcium and phosphate and is mainly used when vitamin D activation or calcium metabolism is impaired, including in kidney and parathyroid disorders.
Alfentanil hydrochloride is a potent, fast-acting opioid analgesic given intravenously. It is mainly used by anaesthetic teams to prevent or control pain during general anaesthesia and surgical procedures.
Alfuzosin hydrochloride is an alpha-blocker used mainly for urinary symptoms caused by a non-cancerous enlarged prostate. It relaxes muscle around the prostate and bladder outlet, helping urine flow more easily; it does not shrink the prostate.
Alglucosidase alfa is a recombinant form of the acid alpha-glucosidase enzyme deficient in Pompe disease. It is used as long-term enzyme replacement therapy to reduce glycogen accumulation and support muscle, breathing and heart function.
Alimemazine tartrate is a sedating phenothiazine antihistamine. Selected products are licensed for urticaria and itching, and for pre-anaesthetic sedation in young children; age and formulation restrictions vary by product.
Alirocumab is an injectable monoclonal antibody that lowers LDL cholesterol by blocking PCSK9. It is used when cholesterol remains high despite other treatment, when statins cannot be used, and to reduce cardiovascular risk in adults with established atherosclerotic disease.
Alitretinoin is an oral retinoid related to vitamin A, licensed for adults with severe chronic hand eczema that has not responded to potent topical corticosteroids.
This combination is a local haemorrhoid treatment. Lidocaine numbs the affected area to relieve pain and irritation, while allantoin is included to support healing. The ointment is licensed for external haemorrhoids and the suppositories for rectal use.
Allopurinol is a xanthine-oxidase inhibitor that lowers uric acid production. It helps prevent gout and certain kidney stones and reduces harmful uric acid accumulation in some high-cell-turnover conditions.
Almotriptan is a triptan used to relieve the headache phase of a migraine attack, with or without aura. It treats an attack after it starts and does not prevent future migraines.
Alogliptin benzoate provides alogliptin, a DPP-4 inhibitor that helps lower blood glucose. It is licensed for adults with type 2 diabetes alongside other glucose-lowering treatments when diet, exercise and existing treatment have not provided adequate control.
This fixed-combination tablet contains alogliptin, a DPP-4 inhibitor, and metformin, a biguanide. It is licensed for adults with type 2 diabetes when metformin alone is insufficient, when both ingredients are already used, or in certain combinations with insulin or pioglitazone.
Alpelisib is an oral targeted anticancer treatment that blocks PI3K-alpha. In the UK, it is licensed with fulvestrant for certain PIK3CA-mutated, hormone receptor-positive, HER2-negative advanced breast cancers that have progressed after endocrine-based therapy.
Alprazolam is a benzodiazepine that enhances inhibitory GABA signalling in the brain. The selected UK product is licensed for short-term symptomatic treatment of severe, disabling or extremely distressing anxiety in adults.
Alprostadil is a form of prostaglandin E1 that relaxes smooth muscle and widens blood vessels. It is used for erectile dysfunction in adults and, as a specialist hospital infusion, to temporarily keep the ductus arteriosus open in babies with certain congenital heart defects.
Alteplase is a thrombolytic treatment that dissolves fibrin-rich blood clots. In hospital, it is used for selected patients with acute ischaemic stroke, heart attack or a large pulmonary embolism causing circulatory instability.