alanine + arginine + aspartic acid + 17 other active ingredients at a glance
Medicine class
Combined parenteral nutrition solution
How it is given
Infused into a central vein under specialist supervision
Who it is licensed for
Adults, adolescents and children older than 2 years
Electrolytes
Almost electrolyte-free; required electrolytes are supplied separately
What is alanine + arginine + aspartic acid + 17 other active ingredients used for?
Licensed to supply energy, amino acids, essential omega-3 and omega-6 fatty acids and fluid during parenteral nutrition when nutrition through the digestive tract is impossible, insufficient or contraindicated.
Moderate to severe catabolic states requiring intravenous nutrition
Parenteral nutrition for adults, adolescents and children older than 2 years
Intradialytic parenteral nutrition may be considered for selected non-acutely ill, malnourished dialysis patients when nutritional counselling or oral supplements have been ineffective
How does alanine + arginine + aspartic acid + 17 other active ingredients work?
Amino acids provide building blocks for protein synthesis and tissue maintenance. Glucose and triglycerides provide energy so amino acids can be used for repair rather than fuel; the lipid mixture also supplies essential omega-3 and omega-6 fatty acids. Intravenous delivery makes these nutrients immediately available without using the digestive tract.
How to take alanine + arginine + aspartic acid + 17 other active ingredients
This infusion is prepared and administered by trained staff through a central venous line. The three chambers must be mixed before use, brought to room temperature and checked for leaks, particles, discolouration or separation.
Use strict aseptic technique and a suitable infusion set.
Do not use a damaged bag or an emulsion that is not uniformly milky white after mixing.
Do not add medicines or nutrients unless compatibility has been established.
The container is single-use and must not be reconnected once partly used.
Whether eating or drinking is permitted depends on the underlying condition and clinical plan.
alanine + arginine + aspartic acid + 17 other active ingredients side effects
Common or expected effects
- Nausea, vomiting or reduced appetite (listed as uncommon)
- Headache, drowsiness, flushing, sweating or chills (listed as rare)
- Changes in blood pressure or pain in the chest, back, bones or lower back (listed as rare)
Get urgent medical advice
- Allergic reaction with rash, breathing difficulty or swelling of the face, mouth or throat
- Shortness of breath or blue-grey skin
- Severe disturbances of blood glucose, blood fats or acid–base balance
- Fat overload syndrome, which may include fever, liver enlargement, jaundice, abnormal blood counts, bleeding problems or reduced consciousness
- Pulmonary oedema or marked fluid overload
- Possible line infection with fever, shivering or an inflamed line site
alanine + arginine + aspartic acid + 17 other active ingredients in pregnancy
Parenteral nutrition can be necessary during pregnancy, but product-specific pregnancy data are absent or limited. Use requires careful specialist assessment of maternal nutritional need and potential risks.
alanine + arginine + aspartic acid + 17 other active ingredients while breastfeeding
Although harmful effects from components entering breast milk are not anticipated at therapeutic exposure, the product information does not recommend breastfeeding while the mother is receiving parenteral nutrition. Discuss feeding options with the specialist team.
alanine + arginine + aspartic acid + 17 other active ingredients interactions
The nutrition team should review medicines, other infusions and all nutrient sources before administration.
Coumarin anticoagulants, including warfarin
Vitamin K1 naturally present in soya-bean oil may alter anticoagulant effect, so coagulation control requires close monitoring.
Heparin
It can temporarily change lipoprotein-lipase activity and triglyceride clearance.
Insulin
It may affect lipid metabolism, although the product information considers this interaction of limited clinical importance.
Common questions about alanine + arginine + aspartic acid + 17 other active ingredients
Answers are fully visible for fast scanning and source review.
What is this infusion used for?
It supplies amino acids, glucose, lipids and fluid intravenously when oral or tube feeding cannot meet nutritional needs or cannot be used.
Is this complete parenteral nutrition?
It supplies major nutrients and fluid, but electrolytes, vitamins and trace elements must be assessed and supplied separately where required.
Sources
These sources were used to prepare and review this medicine page.
Prepared and reviewed by the iatroX editorial team.