alanine + arginine + calcium chloride + 18 other active ingredients at a glance
Medicine class
Intravenous parenteral nutrition mixture containing amino acids, glucose and electrolytes.
Usual role
Nutritional support when oral or enteral feeding cannot meet nutritional needs.
Administration
Given into a vein by trained healthcare professionals, usually through central venous access because the mixed solution is highly concentrated.
Important limitation
The supplied product does not contain lipid, vitamins or trace elements; these may be added when clinically required and compatible.
What is alanine + arginine + calcium chloride + 18 other active ingredients used for?
Used for parenteral nutrition when oral or enteral feeding is impossible, insufficient or contraindicated.
Provides amino acids, carbohydrate energy and electrolytes directly into the bloodstream.
May form part of longer-term parenteral nutrition, with lipid and other nutrients added when required.
How does alanine + arginine + calcium chloride + 18 other active ingredients work?
Amino acids provide nitrogen for protein synthesis and glucose supplies carbohydrate energy. Electrolytes contribute to electrolyte and acid–base requirements. Intravenous administration bypasses digestion and intestinal absorption.
How to take alanine + arginine + calcium chloride + 18 other active ingredients
Prepared and administered by trained staff through an intravenous line using aseptic technique and an infusion pump.
The seal between the two compartments must be broken and contents mixed before administration.
Do not use damaged, leaking or visibly contaminated bags.
For single use only; partly used bags must not be reconnected.
Only add substances after compatibility and stability have been confirmed.
alanine + arginine + calcium chloride + 18 other active ingredients side effects
Common or expected effects
- Raised blood glucose or glucose in the urine, particularly during severe illness.
- Nausea, vomiting or chills if amino acids are infused too rapidly.
- Pain, redness, warmth or swelling from irritation or inflammation of the infused vein.
Get urgent medical advice
- Hypersensitivity or anaphylaxis, including breathing difficulty, rash, hives or collapse.
- Catheter-related infection or sepsis.
- Pulmonary distress associated with precipitates in the lung circulation.
- Severe fluid overload, electrolyte disturbance, acidosis or hyperosmolar complications.
- Refeeding syndrome in severely undernourished people.
alanine + arginine + calcium chloride + 18 other active ingredients in pregnancy
Safety during pregnancy has not been established in clinical studies. It may be considered when parenteral nutrition is needed, with assessment of maternal nutritional need against potential risks.
alanine + arginine + calcium chloride + 18 other active ingredients while breastfeeding
Safety during breastfeeding has not been established in clinical studies. Use requires an individual benefit–risk assessment by the prescribing and nutrition teams.
alanine + arginine + calcium chloride + 18 other active ingredients interactions
Compatibility must be assessed before sharing an intravenous line or adding anything to the bag.
Ceftriaxone
In newborns aged 28 days or younger, concomitant ceftriaxone is contraindicated. In older patients, it must not be infused simultaneously through the same line because calcium–ceftriaxone precipitates may form.
Potassium-sparing diuretics, ACE inhibitors and angiotensin-II receptor blockers
May increase potassium; use with caution and monitor electrolytes.
Tacrolimus or ciclosporin
May increase the risk of hyperkalaemia with this potassium-containing solution.
Common questions about alanine + arginine + calcium chloride + 18 other active ingredients
Answers are fully visible for fast scanning and source review.
What is it used for?
It provides intravenous nutrition when eating or enteral feeding is impossible, inadequate or contraindicated.
Does it contain fat, vitamins or trace elements?
Not as supplied. Compatible lipid, vitamins and trace elements may be added when clinically required.
How is it administered?
Sources
These sources were used to prepare and review this medicine page.
Prepared and reviewed by the iatroX editorial team.