alanine + arginine + calcium chloride dihydrate + 16 other active ingredients at a glance
Medicine class
Amino acid-based peritoneal dialysis solution
Usual role
Part of peritoneal dialysis for chronic kidney failure, particularly when malnutrition is present
Route
Into the peritoneal cavity only; never into a vein
Key practical point
Use aseptic technique and inspect both the solution and drained fluid
What is alanine + arginine + calcium chloride dihydrate + 16 other active ingredients used for?
The UK-licensed use is:
A non-glucose solution forming part of a peritoneal dialysis regimen for chronic renal failure, particularly in malnourished patients receiving peritoneal dialysis.
How does alanine + arginine + calcium chloride dihydrate + 16 other active ingredients work?
The solution is placed in the peritoneal cavity, where the abdominal lining acts as a dialysis membrane. Diffusion and osmosis move waste, electrolytes and water between the blood and dialysis fluid before the fluid is drained. Many amino acids are absorbed, while lactate is converted towards bicarbonate.
How to take alanine + arginine + calcium chloride dihydrate + 16 other active ingredients
Use only as prescribed and taught by the specialist peritoneal dialysis team.
Administer into the peritoneal cavity; never inject intravenously.
Use aseptic technique throughout the exchange.
Use only clear solution from an undamaged, intact bag; discard after one use.
If warming is advised, use dry heat while the bag remains overwrapped. Do not use hot water or a microwave.
Inspect drained fluid for cloudiness, particles or fibrin and report abnormalities urgently.
Only add another medicine when specifically prescribed and confirmed as compatible.
alanine + arginine + calcium chloride dihydrate + 16 other active ingredients side effects
Common or expected effects
- Nausea or vomiting
- Loss of appetite
- Inflamed stomach or abdominal pain
- Weakness
- Too much or too little body fluid
- Metabolic acidosis
- Low blood potassium
- Anaemia
- Shortness of breath
- Infection
Get urgent medical advice
- Cloudy drained fluid, abdominal pain or fever suggesting peritonitis
- Facial or throat swelling, breathing difficulty or another hypersensitivity reaction
- Marked abdominal distension, pain or breathlessness suggesting overfilling
- Severe fluid or electrolyte disturbance
- Possible encapsulating peritoneal sclerosis, a rare complication of peritoneal dialysis
alanine + arginine + calcium chloride dihydrate + 16 other active ingredients in pregnancy
Clinical information in pregnancy is lacking. It should be used only when the renal and obstetric specialists consider it clearly necessary; dialysis and fluid, electrolyte and nutritional management require specialist review during pregnancy.
alanine + arginine + calcium chloride dihydrate + 16 other active ingredients while breastfeeding
Clinical information during breastfeeding is lacking. Use is not recommended unless the specialist team considers it clearly necessary after assessing the parent, infant and available dialysis options.
alanine + arginine + calcium chloride dihydrate + 16 other active ingredients interactions
Formal interaction studies have not been performed. Important considerations include:
Cardiac glycosides, including digoxin
Changes in potassium, calcium or magnesium can alter effectiveness and increase digitalis toxicity or arrhythmia risk, so close monitoring is required.
Medicines removable by dialysis
Peritoneal dialysis may reduce their blood concentrations, requiring clinical review and monitoring.
Insulin and treatments for hyperglycaemia
Blood glucose should be monitored because treatment requirements may change during peritoneal dialysis.
Common questions about alanine + arginine + calcium chloride dihydrate + 16 other active ingredients
Answers are fully visible for fast scanning and source review.
What is Nutrineal used for?
It is used as part of peritoneal dialysis for chronic kidney failure, particularly when the patient is malnourished.
Does Nutrineal contain glucose?
No. It is an amino acid-based, glucose-free peritoneal dialysis solution.
Can Nutrineal be given into a vein?
Sources
These sources were used to prepare and review this medicine page.
Prepared and reviewed by the iatroX editorial team.