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Pravastatin sodium is a statin that reduces cholesterol production in the liver and helps clear LDL cholesterol from the blood. It is used alongside measures such as diet to treat certain lipid disorders and reduce cardiovascular risk.
Prazosin hydrochloride is a prescription alpha-1 blocker that relaxes blood vessels and smooth muscle. In the UK, it is licensed for hypertension, certain cases of heart failure, Raynaud’s symptoms and urinary obstruction caused by benign prostate enlargement.
Prednisolone acetate is a corticosteroid eye-drop suspension used to reduce inflammation in adults when infection has been excluded.
Prednisone is a systemic corticosteroid that reduces inflammation and suppresses immune activity. The selected UK product contains prednisolone, the active corticosteroid used for inflammatory, allergic, autoimmune and some malignant conditions.
Pregabalin is a prescription gabapentinoid. Standard-release products are licensed in adults for neuropathic pain, add-on treatment for partial seizures and generalised anxiety disorder. Prolonged-release Misabri PR is licensed only for neuropathic pain.
Prilocaine hydrochloride is an amide local anaesthetic that temporarily blocks nerve signals. The selected UK product is used in adults to produce spinal anaesthesia for short surgical procedures.
Primidone is an antiseizure treatment related to barbiturates. It is licensed for several forms of epilepsy and essential tremor, and is partly converted to the active metabolites phenobarbital and PEMA.
Procarbazine hydrochloride is an oral cytotoxic chemotherapy that interferes with cancer-cell growth. It is usually used with other anticancer treatments, particularly for Hodgkin lymphoma, and is also licensed for certain advanced lymphomas and resistant solid tumours.
Prochlorperazine maleate is a phenothiazine anti-sickness treatment that blocks dopamine signalling. Selected buccal products are licensed for nausea and vomiting with migraine previously diagnosed by a doctor.
Prochlorperazine mesilate is a phenothiazine that blocks dopamine activity in the brain. It is commonly used as an anti-sickness treatment; the selected injection is also licensed for schizophrenia and acute mania.
Procyclidine hydrochloride is an antimuscarinic that reduces parkinsonian movement symptoms. Selected oral products are licensed for Parkinson’s disease and troublesome movement effects caused by neuroleptic medicines.
Progesterone is a natural progestogen hormone that changes and supports the womb lining. UK products are used with oestrogen in HRT, for fertility treatment and, in selected high-risk pregnancies, to help prevent preterm birth.
Promazine hydrochloride is a sedating phenothiazine antipsychotic. The selected UK product is used alongside non-medicine measures for short-term management of moderate to severe agitation and restlessness when there is a risk of harm.
Propafenone hydrochloride is a class Ic anti-arrhythmic that changes electrical conduction through the heart. It is used under specialist supervision to treat or prevent certain ventricular and intermittent supraventricular abnormal rhythms, particularly when standard therapy is unsuitable or has failed.
Propamidine isetionate is a topical aromatic diamidine with disinfectant and antifungal activity. The selected UK product is used for minor infections of the eye or eyelid, including conjunctivitis and blepharitis.
Propantheline bromide is an antimuscarinic that reduces involuntary smooth-muscle activity and secretions. It is licensed for adults with gastrointestinal disorders involving smooth-muscle spasm, excessive sweating or enuresis.
Propofol is a short-acting intravenous general anaesthetic. Trained clinicians use it to start or maintain general anaesthesia, provide procedural sedation, or sedate ventilated adults in intensive care.
Propylthiouracil is an antithyroid treatment that reduces thyroid hormone production. It is used to control an overactive thyroid, with blood tests guiding treatment and safety checks.
Protamine sulfate is an antidote that counteracts the blood-thinning effect of heparin. It is given intravenously by healthcare professionals when heparin needs to be neutralised, including around surgery, dialysis or excessive bleeding.
Protein C concentrate is a plasma-derived replacement for a natural blood protein that limits excessive clotting. It is mainly used for serious clotting complications in people with severe congenital protein C deficiency.
Proxymetacaine hydrochloride is a local anaesthetic eye drop that temporarily numbs the eye’s surface. An eye-care professional usually applies it before examinations, pressure measurement or minor eye procedures.
Prucalopride is a gastrointestinal prokinetic that stimulates bowel movement. It is licensed for symptomatic treatment of chronic constipation in adults when laxatives have not provided adequate relief.
Pseudoephedrine hydrochloride is an oral sympathomimetic decongestant. It temporarily reduces swelling inside the nose and sinuses, helping air and mucus move more freely when congestion accompanies conditions such as a cold.
This combines pseudoephedrine, a nasal decongestant, with triprolidine, a sedating antihistamine. It provides short-term symptom relief when congestion occurs alongside sneezing, a runny nose or watery eyes.
Pyrazinamide is an antibiotic used with other antituberculosis antibiotics to treat active tuberculosis caused by Mycobacterium tuberculosis. Resistance develops rapidly if it is used alone.
Pyridostigmine bromide is a reversible cholinesterase inhibitor that improves communication between nerves and muscles. It is mainly used to relieve muscle weakness in myasthenia gravis and is also licensed for paralytic ileus and difficulty passing urine after surgery.
Pyridoxine is a form of vitamin B6 that the body converts into active coenzymes. Prescription tablets are mainly used for vitamin B6 deficiency, certain cases of sideroblastic anaemia, and nerve damage caused by isoniazid.
Pyridoxine hydrochloride is a prescription form of vitamin B6. It replaces deficiency and supports vitamin B6-dependent processes involved in metabolism, haemoglobin formation and nerve function.
Pyrimethamine is an antiprotozoal that disrupts folate metabolism in parasites. Its licensed role is combination treatment of toxoplasmosis, particularly infection affecting the eyes, an unborn baby or people with impaired immunity. Mild or symptom-free infection does not usually require treatment.