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Disopyramide is a prescription antiarrhythmic that alters electrical conduction in the heart. It treats or prevents selected abnormal heart rhythms and can help maintain normal rhythm after cardioversion.
Disopyramide phosphate is a class Ia antiarrhythmic used under specialist supervision to prevent or control selected abnormal heart rhythms.
Disulfiram supports alcohol abstinence alongside psychological and social support. It does not treat withdrawal or directly reduce cravings; it deters drinking by causing a potentially dangerous reaction with alcohol.
A synthetic form of the fat-soluble vitamin E. The selected oral suspension is licensed to correct vitamin E deficiency caused by impaired absorption and acts as an antioxidant in lipid-rich cell membranes.
Dobutamine hydrochloride is an intravenous sympathomimetic that strengthens heart contractions and can increase cardiac output. It is used under close hospital supervision for short-term circulatory support and certain cardiac stress echocardiograms.
Docetaxel is a taxane chemotherapy that disrupts cancer-cell division. It is used alone or with other treatments for several breast, lung, prostate, gastric and head-and-neck cancers.
Docetaxel is a taxane chemotherapy that disrupts cancer-cell division. It may be used alone or with other anticancer treatments for several solid tumours.
Dolutegravir sodium is an antiretroviral that blocks HIV integrase. Used with other antiretrovirals, it controls but does not cure HIV infection.
This fixed combination contains two antiretrovirals that act at different stages of HIV replication. It controls HIV-1 in suitable adults and adolescents but does not cure it.
A fixed combination of two antiretroviral treatments that block HIV-1 replication at different stages. It replaces stable treatment in selected adults whose virus is already suppressed and who meet treatment-history and resistance criteria.
Domperidone is a prescription-only dopamine antagonist used to relieve nausea and vomiting in eligible adults and adolescents.
Domperidone maleate is a prescription-only anti-sickness treatment and peripheral dopamine antagonist. The selected product is licensed to relieve nausea and vomiting.
Donanemab is a monoclonal antibody for mild cognitive impairment or mild dementia caused by Alzheimer’s disease. It can slow clinical decline but does not reverse or cure the disease. UK use is limited to adults with confirmed amyloid pathology and no more than one ApoE4 gene copy.
Donepezil hydrochloride is an acetylcholinesterase inhibitor used to treat symptoms of Alzheimer’s dementia. It may support memory, thinking and everyday functioning, but does not cure Alzheimer’s disease or stop the underlying disease process.
Donepezil hydrochloride monohydrate is an acetylcholinesterase inhibitor used to help symptoms of Alzheimer’s dementia. It may support memory, thinking and everyday functioning, but does not cure Alzheimer’s disease or alter its underlying progression.
Dopamine hydrochloride is a short-acting catecholamine that supports the heart and circulation. It is usually given in hospital for serious hypotension, shock, poor tissue perfusion or low cardiac output.
Doravirine is a non-nucleoside reverse transcriptase inhibitor (NNRTI) used with other antiretrovirals to control HIV-1 when there is no evidence of NNRTI resistance.
A fixed-combination antiretroviral treatment containing one NNRTI and two nucleoside/nucleotide reverse transcriptase inhibitors. It is used for suitable people with HIV-1 whose virus is not resistant to its components.
Dornase alfa is an inhaled recombinant human enzyme that breaks down DNA in thick cystic fibrosis mucus, making airway secretions less sticky and helping lung function.
Dorzolamide hydrochloride is a carbonic anhydrase inhibitor supplied as eye drops. It lowers raised pressure inside the eye in ocular hypertension and certain forms of glaucoma.
This prescription eye-drop combination contains dorzolamide, a carbonic anhydrase inhibitor, and timolol, a beta blocker. It lowers pressure inside the eye in open-angle or pseudoexfoliative glaucoma when a topical beta blocker alone is insufficient.
Dostarlimab helps immune cells recognise and attack cancer cells. It is used in adults with advanced or recurrent endometrial cancer, either with platinum-containing chemotherapy or alone in selected tumours after previous platinum treatment.
Dosulepin hydrochloride is licensed for depressive illness, particularly when an anti-anxiety effect is needed. Because of serious cardiac toxicity in overdose, new treatment is restricted to specialist care when alternatives are unsuitable or ineffective.
Doxapram hydrochloride is a respiratory stimulant given into a vein by a healthcare professional. In the UK, it is licensed to stimulate breathing and arousal after anaesthesia when respiratory activity is reduced.
Doxepin hydrochloride is a sedating tricyclic antidepressant licensed in the selected UK product for depressive illness in adults, particularly when sedation may help.
Doxorubicin hydrochloride is an anthracycline chemotherapy that damages cancer-cell DNA and limits cell division. Conventional and pegylated-liposomal formulations treat different cancers and are not interchangeable.
This combines doxylamine, a sedating antihistamine, with pyridoxine (vitamin B6). It treats nausea and vomiting of pregnancy in adults when lifestyle and dietary measures have not worked.
An oral iron salt used mainly to treat iron-deficiency anaemia. It supplies iron needed to make haemoglobin and red blood cells.
Dronedarone hydrochloride is an antiarrhythmic used under specialist supervision to help maintain a normal rhythm after successful cardioversion in selected clinically stable adults with paroxysmal or persistent atrial fibrillation.
Droperidol is a butyrophenone dopamine-receptor antagonist given by intravenous injection in hospital to prevent or treat nausea and vomiting around surgery, including nausea associated with morphine-based patient-controlled analgesia.
Drospirenone is a progestogen used alone in an oral contraceptive. The selected product prevents pregnancy without containing oestrogen.
Drospirenone + estetrol is a combined oral contraceptive containing an oestrogen and a progestogen. It prevents pregnancy mainly by stopping ovulation.
Combined hormone replacement therapy containing estradiol, an oestrogen, and drospirenone, a progestogen. It relieves postmenopausal oestrogen-deficiency symptoms and has a restricted role in preventing osteoporosis.
Drospirenone + ethinylestradiol is a combined oral contraceptive containing a progestogen and an oestrogen. Its licensed role in the selected UK product is preventing pregnancy.
Dulaglutide is a long-acting GLP-1 receptor agonist that helps lower blood glucose. The selected UK product is used with diet and exercise for insufficiently controlled type 2 diabetes in adults and young people aged 10 years and over.
Dupilumab is a targeted monoclonal antibody that blocks two signals involved in type 2 inflammation. It is used for selected inflammatory conditions affecting the skin, airways and digestive tract when standard treatment has not provided adequate control.
Durvalumab is a monoclonal antibody and immune checkpoint inhibitor used to treat several cancers in adults. Depending on the cancer, stage and biomarkers, it may be used alone or with other anticancer treatments.
Dutasteride is a 5-alpha-reductase inhibitor for moderate to severe symptoms of benign prostatic hyperplasia, a non-cancerous enlarged prostate. It gradually reduces prostate growth and lowers the risk of urinary retention and prostate surgery.
Combines a 5-alpha-reductase inhibitor with an alpha-blocker. It treats moderate to severe symptoms of benign prostate enlargement and reduces the risk of acute urinary retention and prostate-related surgery.
Dydrogesterone is a synthetic progestogen with effects similar to progesterone. It is used for menstrual and progesterone-related disorders and alongside oestrogen in some hormone replacement therapy.
An oral combined hormone replacement therapy (HRT) containing estradiol, an oestrogen, and dydrogesterone, a progestogen. It mainly treats postmenopausal oestrogen-deficiency symptoms; dydrogesterone helps protect the womb lining.