sofosbuvir + velpatasvir · Medicine question

Why is close INR monitoring recommended when sofosbuvir + velpatasvir is taken with vitamin K antagonists?

Name: Why is close INR monitoring recommended when sofosbuvir + velpatasvir is taken with vitamin K antagonists?
Published: 2026-11-08T02:03:13.637Z

iatroX medicinesPublished 8 November 2026

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Close INR monitoring is recommended when sofosbuvir + velpatasvir is taken with vitamin K antagonists because liver function may change during treatment.

Sources for this answer

Sofosbuvir/Velpatasvir Gilead 400 mg/100 mg film coated tablets.Gilead Sciences Ltd · emc · SmPC §4.5 Interaction with other medicinal products · Version 22Document updated 4 July 2025

Sources checked 8 November 2026

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