Answer
Sofosbuvir + velpatasvir increases tenofovir exposure, especially when tenofovir disoproxil fumarate is combined with ritonavir or cobicistat; the safety of this combination has not been established.
Sources for this answer
- Sofosbuvir/Velpatasvir Gilead 400 mg/100 mg film coated tablets.Gilead Sciences Ltd · emc · SmPC §4.4 Special warnings and precautions for use · Version 22Document updated
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