glucose monohydrate + sodium chloride at a glance
Medicine class
Intravenous electrolyte solution with carbohydrate.
How it is given
By intravenous infusion under clinical supervision.
Important monitoring
Fluid balance, blood glucose, sodium and other electrolytes may need checking before and during treatment.
What is glucose monohydrate + sodium chloride used for?
Licensed uses represented by the selected products include:
Treating dehydration associated with sodium and chloride loss when carbohydrate is also required.
Treating hypertonic dehydration.
Providing partial carbohydrate energy.
Acting as a vehicle for compatible medicines or electrolyte concentrates.
In children, the lower-sodium selected formulation is restricted to specialist settings for fluid and electrolyte maintenance.
How does glucose monohydrate + sodium chloride work?
Sodium and chloride help regulate extracellular fluid and electrolyte balance. Glucose is metabolised for energy. The remaining infused water may then act as a hypotonic fluid and lower blood sodium in susceptible patients.
How to take glucose monohydrate + sodium chloride
A doctor or nurse gives the solution through a vein. The container and solution are inspected before use, sterile equipment is used and partially used containers are discarded. Added medicines require confirmed compatibility.
It is not taken by mouth, so food does not directly affect administration.
Tell staff promptly if the infusion site becomes painful, red or swollen.
It should not be given if the solution contains particles or the container is damaged.
glucose monohydrate + sodium chloride side effects
Common or expected effects
- Infusion-site pain or irritation, inflamed veins, fever, chills, rash or itching; frequency is not known.
- High blood glucose or disturbances of sodium, potassium and other electrolytes.
- Swelling or worsening congestion from excess fluid.
Get urgent medical advice
- Acute hyponatraemia causing headache, nausea, confusion, marked drowsiness, seizures or brain swelling.
- Severe hypersensitivity or anaphylaxis.
- Fluid overload causing pulmonary oedema or serious breathlessness.
- Severe hyperglycaemia or major electrolyte and acid–base disturbance.
glucose monohydrate + sodium chloride in pregnancy
Use requires individual clinical assessment because product information differs. Particular caution is needed during labour: intravenous glucose may affect fetal and newborn glucose balance, while concurrent oxytocin can increase hyponatraemia risk.
glucose monohydrate + sodium chloride while breastfeeding
The lower-sodium selected formulation may be used after weighing individual benefits and risks. The other selected product advises caution because clinical data are limited. Any added medicine must be assessed separately.
glucose monohydrate + sodium chloride interactions
The clinical team should review medicines affecting glucose, sodium or water balance and check compatibility with anything added to the infusion.
Oxytocin, desmopressin, terlipressin and other vasopressin-enhancing medicines
May reduce electrolyte-free water excretion and increase hospital-acquired hyponatraemia risk.
Diuretics and oxcarbazepine
Can further increase hyponatraemia risk; some diuretics may also contribute to low potassium.
Common questions about glucose monohydrate + sodium chloride
Answers are fully visible for fast scanning and source review.
Does this infusion provide complete nutrition?
No. It supplies carbohydrate energy but not complete nutrition, protein or all required electrolytes and micronutrients.
Can it raise blood sugar?
Yes. Hyperglycaemia can occur, especially with impaired glucose tolerance, so blood glucose may require monitoring.
Sources
These sources were used to prepare and review this medicine page.
Prepared and reviewed by the iatroX editorial team.