glucose + magnesium chloride hexahydrate + potassium chloride + sodium acetate trihydrate + sodium chloride + sodium gluconate at a glance
Medicine class
Intravenous electrolyte solution with carbohydrate
Usual role
Fluid replacement, including during surgery, with a source of glucose
Administration
Given by trained healthcare professionals through an intravenous infusion
Key monitoring
Fluid balance, blood glucose, electrolytes and acid–base status
What is glucose + magnesium chloride hexahydrate + potassium chloride + sodium acetate trihydrate + sodium chloride + sodium gluconate used for?
UK-licensed uses include:
Replacing fluid while supplying carbohydrate, including after burns, head injury, fractures, infection or peritoneal irritation
Replacing fluid during an operation
Managing mild to moderate metabolic acidosis, including when lactate metabolism is impaired
How does glucose + magnesium chloride hexahydrate + potassium chloride + sodium acetate trihydrate + sodium chloride + sodium gluconate work?
Water and electrolytes expand fluid outside cells, including circulating blood volume. Glucose supplies carbohydrate for cellular energy. Acetate and gluconate are converted to bicarbonate, producing an alkalinising effect.
How to take glucose + magnesium chloride hexahydrate + potassium chloride + sodium acetate trihydrate + sodium chloride + sodium gluconate
A doctor or nurse gives this solution intravenously using sterile equipment. The solution must be clear, its seal intact and any added medicine checked for compatibility. Because it is hyperosmotic, it should not be administered through a peripheral vein.
Tell staff promptly if the line becomes painful, red, swollen, wet or starts leaking.
Do not handle, disconnect or restart the infusion yourself.
It must not run through the same infusion equipment as whole blood or red blood cells.
glucose + magnesium chloride hexahydrate + potassium chloride + sodium acetate trihydrate + sodium chloride + sodium gluconate side effects
Get urgent medical advice
- Hypersensitivity or infusion reaction, potentially causing facial or throat swelling, breathing difficulty, wheezing, low blood pressure or chest symptoms
- Fluid overload, which may cause swelling or difficulty breathing
- High potassium or abnormal sodium levels, potentially causing weakness, abnormal heart rhythm, confusion or seizures
- High blood glucose
- Inflammation, thrombosis, infection or leakage into tissues at the infusion site
glucose + magnesium chloride hexahydrate + potassium chloride + sodium acetate trihydrate + sodium chloride + sodium gluconate in pregnancy
Adequate pregnancy data are unavailable. Clinicians should assess the expected benefit and potential risk and monitor fluid balance and blood chemistry. During labour, concurrent oxytocin may increase the risk of hyponatraemia.
glucose + magnesium chloride hexahydrate + potassium chloride + sodium acetate trihydrate + sodium chloride + sodium gluconate while breastfeeding
Adequate data in breastfeeding women are unavailable. Use requires an individual clinical assessment, particularly if another medicine will be added to the infusion.
glucose + magnesium chloride hexahydrate + potassium chloride + sodium acetate trihydrate + sodium chloride + sodium gluconate interactions
The clinical team should review all medicines because the solution contains glucose, potassium, magnesium, sodium, acetate and gluconate.
Potassium-sparing diuretics
Amiloride, spironolactone, triamterene and related medicines can substantially increase the risk of hyperkalaemia.
ACE inhibitors, angiotensin-II receptor blockers, tacrolimus or ciclosporin
Concurrent use can increase blood potassium, especially when kidney function is impaired.
Medicines associated with hyponatraemia
Diuretics, NSAIDs, SSRIs, antipsychotics, opioids, antiepileptics, oxytocin and some chemotherapy may increase the risk of low sodium.
Common questions about glucose + magnesium chloride hexahydrate + potassium chloride + sodium acetate trihydrate + sodium chloride + sodium gluconate
Answers are fully visible for fast scanning and source review.
Why is it given during surgery?
It can replace extracellular fluid during an operation while supplying carbohydrate.
Does it contain sugar?
Yes. It contains glucose, which supplies carbohydrate and can raise blood glucose.
Sources
These sources were used to prepare and review this medicine page.
Prepared and reviewed by the iatroX editorial team.