calcium chloride + glucose, anhydrous + glucose monohydrate + magnesium chloride + sodium chloride + sodium lactate at a glance
Medicine class
Glucose-based, lactate-buffered solution for peritoneal dialysis.
Administration
For intraperitoneal use through a peritoneal dialysis catheter; it must not be given intravenously.
Key safety check
Use only clear solution from an intact bag and inspect drained fluid for cloudiness or fibrin.
Potassium content
Contains no potassium, so blood potassium requires monitoring.
What is calcium chloride + glucose, anhydrous + glucose monohydrate + magnesium chloride + sodium chloride + sodium lactate used for?
Licensed uses when peritoneal dialysis is employed include:
Acute or chronic kidney failure.
Severe fluid retention.
Electrolyte disturbances.
Some drug intoxications when a more appropriate treatment is unavailable.
Supporting calcium and phosphate control in people with renal failure receiving calcium- or magnesium-containing phosphate binders.
How does calcium chloride + glucose, anhydrous + glucose monohydrate + magnesium chloride + sodium chloride + sodium lactate work?
The peritoneal membrane acts as a filter between blood vessels and dialysis fluid. Waste moves into the fluid by diffusion, while glucose draws excess water from the blood. Lactate acts as a bicarbonate precursor, and the electrolytes support fluid, electrolyte and acid–base balance.
How to take calcium chloride + glucose, anhydrous + glucose monohydrate + magnesium chloride + sodium chloride + sodium lactate
Use only as trained by the specialist peritoneal dialysis team and only through the abdominal catheter.
Maintain aseptic technique during connection, infusion and drainage.
If warming is advised, use dry heat or the designated warming plate; never use water or a microwave.
Do not use a cloudy, discoloured, leaking or damaged bag, or one with broken seals.
Remove the overpouch immediately before use. Use each bag once and discard any remainder.
Inspect drained fluid for cloudiness or fibrin and report abnormalities immediately.
Add another medicine only when specifically prescribed and after compatibility has been checked.
calcium chloride + glucose, anhydrous + glucose monohydrate + magnesium chloride + sodium chloride + sodium lactate side effects
Common or expected effects
- The selected product information does not classify any effects as common. Effects reported with unknown frequency include nausea, vomiting, diarrhoea, constipation, abdominal discomfort or swelling, muscle cramps, itching or rash, infusion-site pain, tiredness, fluid retention or dehydration, and low blood pressure.
Get urgent medical advice
- Peritonitis or catheter-related infection: cloudy drainage, abdominal pain, fever or shivering.
- Fluid overload or excessive fluid removal: breathlessness, swelling, dizziness, fainting or marked blood-pressure changes.
- Electrolyte disturbances, particularly low potassium, which may cause weakness, twitching or an abnormal heartbeat.
- Severe hypersensitivity, including anaphylactic-type reactions.
- Stevens–Johnson syndrome, with blistering of the skin, mouth, eyes or genitals.
- Encapsulating peritoneal sclerosis, a rare complication associated with persistent abdominal inflammation, pain, swelling or vomiting.
calcium chloride + glucose, anhydrous + glucose monohydrate + magnesium chloride + sodium chloride + sodium lactate in pregnancy
The selected product information does not recommend use during pregnancy because clinical data are limited. Pregnancy while requiring dialysis needs early specialist obstetric and renal review. Do not stop essential dialysis without medical direction.
calcium chloride + glucose, anhydrous + glucose monohydrate + magnesium chloride + sodium chloride + sodium lactate while breastfeeding
It is unknown whether relevant metabolites enter human milk, and risk to a breastfed infant cannot be excluded. The renal and maternity teams should weigh the benefits of breastfeeding against the need for this dialysis solution.
calcium chloride + glucose, anhydrous + glucose monohydrate + magnesium chloride + sodium chloride + sodium lactate interactions
Peritoneal dialysis and this glucose- and lactate-containing solution can affect other treatments.
Dialysable medicines
Peritoneal dialysis may lower their blood concentrations, so clinical effect or medicine levels may require review.
Cardiac glycosides, including digoxin
Changes in potassium, calcium or magnesium can increase toxicity and abnormal-heartbeat risk; monitor electrolytes and clinical response closely.
Insulin and other glucose-lowering treatments
Glucose absorption from the dialysis fluid can alter blood-sugar control, particularly when treatment starts or changes.
Common questions about calcium chloride + glucose, anhydrous + glucose monohydrate + magnesium chloride + sodium chloride + sodium lactate
Answers are fully visible for fast scanning and source review.
Is it injected into a vein?
No. It is placed into the peritoneal cavity through a dialysis catheter and must not be administered intravenously.
Why does it contain glucose?
Glucose creates an osmotic gradient that draws excess water from the blood into the dialysis fluid.
Sources
These sources were used to prepare and review this medicine page.
Prepared and reviewed by the iatroX editorial team.