golimumab · Medicine question

Why is combining golimumab with anakinra not recommended?

iatroX medicinesPublished 8 November 2026

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Combining golimumab with anakinra is not recommended because anakinra plus another TNF blocker, etanercept, caused serious infections and neutropenia without added clinical benefit in studies, and similar toxicities may occur with golimumab.

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Simponi 50 mg solution for injection in pre filled syringeJanssen-Cilag Ltd (a Johnson & Johnson Company) · emc · SmPC §4.4 Special warnings and precautions for use · Version 41Document updated 13 July 2026

Sources checked 8 November 2026

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