For which adults with rheumatoid arthritis is Simponi (golimumab) indicated in combination with methotrexate?

Simponi (golimumab) with methotrexate is indicated for adults with moderate to severe active rheumatoid arthritis inadequately responsive to disease-modifying antirheumatic drug therapy including methotrexate, or severe, active and progressive rheumatoid arthritis not previously treated with methotrexate.