golimumab · Medicine question

Can golimumab reactivate hepatitis B in chronic carriers?

iatroX medicinesPublished 8 November 2026

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Yes, hepatitis B reactivation has occurred in chronic carriers (surface antigen positive) receiving TNF antagonists including golimumab, and some cases have been fatal.

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Simponi 50 mg solution for injection in pre filled syringeJanssen-Cilag Ltd (a Johnson & Johnson Company) · emc · SmPC §4.4 Special warnings and precautions for use · Version 41Document updated 13 July 2026

Sources checked 8 November 2026

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