Answer
Lens clouding has been reported in children exposed to ivacaftor-containing treatments, so baseline and follow-up examinations are recommended.
Sources for this answer
- Orkambi 150 mg/188 mg granules in sachetemc · SmPC Current selected SmPC · Version 10
- Orkambi 200 mg/125 mg film coated tabletsemc · SmPC Current selected SmPC · Version 19