Answer
Yes. It can reduce the effectiveness of hormonal pills, injections, patches and implants, which should not be relied upon as effective contraception during treatment.
Sources for this answer
- Orkambi 150 mg/188 mg granules in sachet — Current selected SmPCemc · Summary of Product Characteristics
- Orkambi 200 mg/125 mg film coated tablets — Current selected SmPCemc · Summary of Product Characteristics
General medicine information. Follow the instructions for your own medicine and speak to a pharmacist or clinician about your individual circumstances.