tapentadol hydrochloride · Medicine question

What sleep-related breathing disorders can occur with Palexia SR (tapentadol hydrochloride)?

Name: What sleep-related breathing disorders can occur with Palexia SR (tapentadol hydrochloride)?
Published: 2026-11-08T02:02:08.182Z

iatroX medicinesPublished 8 November 2026

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Palexia SR (tapentadol hydrochloride) can cause central sleep apnea and sleep-related hypoxemia, with central sleep apnea risk increasing in a dose-dependent manner.

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Palexia SR 250 mg prolonged-release tabletsGrunenthal Ltd · emc · SmPC §4.4 Special warnings and precautions for use · Version 10Document updated 13 January 2026

Sources checked 8 November 2026

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