Answer
Combining Palexia SR (tapentadol hydrochloride) with benzodiazepines increases the risk of sedation, respiratory depression, coma and death through additive central nervous system depression.
Sources for this answer
- Palexia SR 250 mg prolonged-release tabletsGrunenthal Ltd · emc · SmPC §4.5 Interaction with other medicinal products · Version 10Document updated
Sources checked