Answer
In rats, dapagliflozin, a component of Xigduo (dapagliflozin/metformin), caused toxicity to the developing kidney during the period corresponding to the second and third trimesters of human pregnancy.
Sources for this answer
- Xigduo 5 mg/850 mg film-coated tabletsAstraZeneca UK Limited · emc · SmPC §4.6 Fertility, pregnancy and lactation · Version 27Document updated
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