Answer
Combining piperacillin + tazobactam with vancomycin is associated with an increased incidence of acute kidney injury compared with vancomycin alone, with some studies reporting that the interaction is vancomycin dose-dependent.
Sources for this answer
- Piperacillin/Tazobactam 4 g/0.5 g powder for solution for infusionReig Jofre UK Ltd · emc · SmPC §4.5 Interaction with other medicinal products · Version 2Document updated
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