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Medicines tacrolimusQuestion & answer

tacrolimus · Medicine question

What effects on male fertility were observed in rats given tacrolimus?

iatroX medicinesPublished 8 November 2026

The answer

Answer

Tacrolimus adversely affected male fertility in rats, with reduced sperm counts and motility.

Sources for this answer

Prograf 5mg/ml Concentrate for Solution for Infusion (UK)Astellas Pharma Ltd · emc · SmPC §4.6 Fertility, pregnancy and lactation · Version 29Document updated 17 March 2026

Sources checked 8 November 2026

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tacrolimus

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