olodaterol hydrochloride + tiotropium bromide monohydrate at a glance
Medicine class
Long-acting muscarinic antagonist plus long-acting beta₂ agonist (LAMA/LABA).
Licensed use
Maintenance bronchodilator treatment for symptomatic COPD in adults.
Device
Inhalation solution in a cartridge for the reusable Respimat soft-mist inhaler.
Not a rescue inhaler
Do not use for a sudden episode of wheezing or breathlessness.
What is olodaterol hydrochloride + tiotropium bromide monohydrate used for?
The selected product is licensed for:
Maintenance bronchodilation to relieve symptoms in adults with COPD.
It is not licensed for asthma or relief of acute bronchospasm.
How does olodaterol hydrochloride + tiotropium bromide monohydrate work?
Tiotropium blocks muscarinic receptors that can tighten airway muscle. Olodaterol stimulates beta₂ receptors, also relaxing airway muscle. Together, these actions widen the airways.
olodaterol hydrochloride + tiotropium bromide monohydrate preparations and strengths
Inhaled preparation
Route: Inhaled
Strengths: 2.5 micrograms + 2.5 micrograms
How to take olodaterol hydrochloride + tiotropium bromide monohydrate
Use only by inhalation through the reusable Respimat device, exactly as prescribed. Before first use, insert and prepare the cartridge as shown in the pack leaflet. A healthcare professional should check your technique.
Breathe out slowly away from the inhaler. Seal your lips around the mouthpiece without covering the air vents, then press the dose-release button while taking a slow, deep breath.
Avoid directing the mist into the eyes.
Clean the mouthpiece, including the metal section inside it, with a damp cloth or tissue.
Follow the leaflet's priming instructions if the inhaler has not been used for an extended period.
The inhaler is for one person's use.
olodaterol hydrochloride + tiotropium bromide monohydrate side effects
Common or expected effects
- Headache or dizziness
- Cough or hoarse voice
- Faster heartbeat
Get urgent medical advice
- Immediate allergic reaction, including facial or throat swelling and breathing difficulty
- Paradoxical bronchospasm: sudden chest tightness, coughing, wheezing or breathlessness after inhalation
- Eye pain, red eye, blurred vision or coloured halos suggesting acute narrow-angle glaucoma
- Difficulty passing urine or inability to urinate
- New or significant chest pain, marked palpitations or abnormal heartbeat
- Severe constipation with abdominal swelling or absent bowel movements
olodaterol hydrochloride + tiotropium bromide monohydrate in pregnancy
Product-specific pregnancy data are limited, especially for olodaterol, and the product information advises avoiding the combination as a precaution. Pregnancy or plans for pregnancy should prompt review with a prescriber or respiratory specialist rather than abrupt discontinuation.
olodaterol hydrochloride + tiotropium bromide monohydrate while breastfeeding
Tiotropium inhalers, including combinations containing olodaterol, can be used while breastfeeding because infant exposure is expected to be very low. The product information notes no clinical lactation data and recommends weighing the benefits of breastfeeding and treatment; discuss individual circumstances with the prescriber.
olodaterol hydrochloride + tiotropium bromide monohydrate interactions
Check prescription, non-prescription and herbal products with a pharmacist or prescriber. Important examples include:
Other anticholinergic medicines
May increase dry mouth, constipation, blurred vision or urinary retention.
Other long-acting beta₂ agonists
May duplicate treatment and increase beta₂-agonist adverse effects.
Beta-blockers, including some glaucoma eye drops
May reduce olodaterol's bronchodilator effect and can provoke bronchospasm; cardioselective agents still require caution.
Common questions about olodaterol hydrochloride + tiotropium bromide monohydrate
Answers are fully visible for fast scanning and source review.
Is this a steroid inhaler?
No. It combines two long-acting bronchodilators—a LAMA and a LABA—and contains no inhaled corticosteroid.
Can it treat a sudden COPD attack?
No. It is maintenance treatment, not a rescue inhaler.
Can it be used for asthma?
Sources
These sources were used to prepare and review this medicine page.
Prepared and reviewed by the iatroX editorial team.