Answer
After inhalation, olodaterol in Spiolto Respimat binds to and activates airway beta₂-adrenoceptors, stimulating intracellular adenyl cyclase to increase cyclic adenosine monophosphate (cAMP), which relaxes airway smooth muscle cells and causes bronchodilation.
Sources for this answer
- Spiolto Respimat 2.5 microgram/2.5 microgram, inhalation solutionBoehringer Ingelheim Limited · emc · SmPC §5.1 Pharmacodynamic properties · Version 9Document updated
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