lidocaine hydrochloride + phenylephrine hydrochloride at a glance
Medicine class
Local anaesthetic with a sympathomimetic vasoconstrictor
Usual setting
Applied to nasal or throat tissue by a doctor or nurse before a procedure
Children
The selected product is not recommended for children younger than 12 years
What is lidocaine hydrochloride + phenylephrine hydrochloride used for?
The selected product is licensed for:
Preparing the nasal lining for surgery or endoscopy
Helping remove a foreign body from the nose
Numbing the throat before direct or indirect laryngoscopy
How does lidocaine hydrochloride + phenylephrine hydrochloride work?
Lidocaine blocks sodium channels in nearby nerves, temporarily preventing pain signals. Phenylephrine stimulates mainly alpha-1 receptors, narrowing local blood vessels and helping reduce swelling and bleeding.
How to take lidocaine hydrochloride + phenylephrine hydrochloride
A doctor or nurse applies the solution inside the nose or throat using its pump spray. Throat or mouth numbness can affect swallowing and increase accidental biting, so follow the clinical team's instructions about eating and drinking afterwards.
It is for nasal or throat tissue, not for swallowing or self-injection.
Each container is for one patient and one procedure session; any remaining solution is discarded.
lidocaine hydrochloride + phenylephrine hydrochloride side effects
Common or expected effects
- Headache
- Temporary tongue, mouth or throat numbness that may affect swallowing or increase accidental biting
Get urgent medical advice
- Breathing difficulty, severe swelling or another suspected allergic reaction
- Seizure, profound drowsiness, confusion, respiratory depression or loss of consciousness
- Severe hypertension, chest pain, fainting, marked palpitations or an abnormal heartbeat
- Inability to pass urine
lidocaine hydrochloride + phenylephrine hydrochloride in pregnancy
The selected combination product should not be administered during pregnancy.
lidocaine hydrochloride + phenylephrine hydrochloride while breastfeeding
The selected combination product should not be administered while breastfeeding.
lidocaine hydrochloride + phenylephrine hydrochloride interactions
The clinical team should review all prescribed, pharmacy and topical products before administration.
Irreversible monoamine oxidase inhibitors
Current or recent use is contraindicated because phenylephrine may cause a dangerous hypertensive reaction.
Other sympathomimetics
Concurrent use by oral, nasal, eye or other routes can cause additive cardiovascular effects and is contraindicated for the selected product.
Beta blockers and other antihypertensives
Phenylephrine may oppose blood-pressure treatment or cause severe cardiovascular reactions; propranolol may also increase lidocaine toxicity.
Common questions about lidocaine hydrochloride + phenylephrine hydrochloride
Answers are fully visible for fast scanning and source review.
What is it used for?
It numbs nasal or throat tissue and constricts local blood vessels before specified nasal procedures or laryngoscopy. It may also help with removal of a nasal foreign body.
How is it given?
A doctor or nurse sprays it onto the tissue inside the nose or throat.
Can I swallow normally afterwards?
Sources
These sources were used to prepare and review this medicine page.
Prepared and reviewed by the iatroX editorial team.