Answer
Yes. Systemically absorbed phenylephrine can cause hypertension, pulse changes, palpitations, arrhythmias or chest pain.
Sources for this answer
- Lidocaine Hydrochloride 5% w/v and Phenylephrine Hydrochloride 0.5% w/v Topical Solution — Current selected SmPCemc · Summary of Product Characteristics
General medicine information. Follow the instructions for your own medicine and speak to a pharmacist or clinician about your individual circumstances.