hydrocortisone acetate + miconazole nitrate at a glance
Medicine class
Topical imidazole antifungal combined with a mild corticosteroid.
Licensed uses
Inflamed athlete’s foot and inflamed candidal intertrigo affecting skin folds.
Application
For external use on affected skin; rub in gently and avoid the eyes and mucous membranes.
What is hydrocortisone acetate + miconazole nitrate used for?
This product is licensed for fungal skin infections where inflammation is also present.
Athlete’s foot with inflammation.
Candidal intertrigo—an inflamed Candida infection in skin folds.
How does hydrocortisone acetate + miconazole nitrate work?
Miconazole disrupts fungal cell membranes and also acts against some Gram-positive bacteria. Hydrocortisone reduces inflammation, easing redness, swelling and itching.
How to take hydrocortisone acetate + miconazole nitrate
Use only on the skin. Clean and dry the affected area, apply as directed and rub in gently. Wash your hands afterwards unless they are being treated. Keep it away from the face, eyes and mucous membranes. Avoid broken skin, large areas and covered applications unless specifically prescribed.
Do not share towels or flannels where infection may spread.
Prefer cotton clothing where fabric contacts the cream because some synthetic materials can be damaged.
Avoid contact with latex condoms and diaphragms because the cream may damage them.
hydrocortisone acetate + miconazole nitrate side effects
Common or expected effects
- No adverse reaction occurred in at least 1% of participants across the cited clinical trials. Uncommon local effects included burning, irritation, itching and hives.
- Other reported effects include redness, rash, contact dermatitis, inflammation or lighter skin at the application site.
- Blurred vision has been reported and needs medical assessment.
Get urgent medical advice
- Severe allergic reaction, including angioedema or anaphylaxis: stop using it and obtain emergency help.
- Unexpected bleeding or bruising while taking warfarin or another vitamin K antagonist: stop using it and seek urgent medical advice.
hydrocortisone acetate + miconazole nitrate in pregnancy
Product-specific pregnancy data are limited, and the product information advises avoiding this combination as a precaution. Discuss its use with a prescriber or pharmacist. Avoid large areas and covered applications. Evidence for topical corticosteroids generally has not identified known pregnancy risks when used as directed.
hydrocortisone acetate + miconazole nitrate while breastfeeding
The product information recommends caution because evidence for this combination is limited. Specialist UK guidance considers topical hydrocortisone, including antimicrobial combinations, compatible with breastfeeding for full-term healthy infants because maternal absorption is low. Avoid large or covered areas, prevent infant contact with treated skin, and wash cream from the breast or nipple before feeding.
hydrocortisone acetate + miconazole nitrate interactions
Systemic absorption is limited, so clinically important interactions are uncommon. The main product-specific concern is anticoagulation.
Warfarin and other vitamin K antagonists
Topical miconazole may increase the anticoagulant effect; INR and signs of bleeding require close monitoring.
Common questions about hydrocortisone acetate + miconazole nitrate
Answers are fully visible for fast scanning and source review.
What is hydrocortisone acetate + miconazole nitrate used for?
It treats athlete’s foot or candidal intertrigo when the fungal infection is accompanied by redness, swelling or itching.
Is it an antifungal or a steroid?
It is both: miconazole treats susceptible fungi, while hydrocortisone reduces inflammation.
Can it be used for ringworm?
Sources
These sources were used to prepare and review this medicine page.
Prepared and reviewed by the iatroX editorial team.