calcium chloride dihydrate + glucose monohydrate + magnesium chloride hexahydrate + potassium chloride + sodium chloride + sodium hydrogen carbonate at a glance
Medicine class
Bicarbonate-buffered haemofiltration replacement solution
Usual role
Supports continuous haemofiltration for acute kidney failure
Administration
Given into the extracorporeal blood circuit by trained hospital staff; it is not swallowed
Preparation
The two chambers must be mixed and the solution checked for damage, particles or precipitation
What is calcium chloride dihydrate + glucose monohydrate + magnesium chloride hexahydrate + potassium chloride + sodium chloride + sodium hydrogen carbonate used for?
Licensed as a replacement solution for continuous haemofiltration.
Acute kidney failure of any cause when continuous haemofiltration is required
How does calcium chloride dihydrate + glucose monohydrate + magnesium chloride hexahydrate + potassium chloride + sodium chloride + sodium hydrogen carbonate work?
Haemofiltration removes water, waste products and electrolytes from blood. This solution replaces the removed fluid with balanced electrolytes and bicarbonate, helping maintain blood volume, osmotic balance and acid–base status.
How to take calcium chloride dihydrate + glucose monohydrate + magnesium chloride hexahydrate + potassium chloride + sodium chloride + sodium hydrogen carbonate
This hospital-only solution is used within a continuous haemofiltration circuit under an experienced clinician’s direction. It must not be swallowed or self-administered.
Use only after both chambers have been thoroughly mixed.
Do not use a damaged bag or a cloudy solution, or one containing visible particles.
Do not add another medicine unless compatibility has been assessed after mixing.
calcium chloride dihydrate + glucose monohydrate + magnesium chloride hexahydrate + potassium chloride + sodium chloride + sodium hydrogen carbonate side effects
Get urgent medical advice
- Excess or insufficient body fluid, causing swelling, breathlessness, blood-pressure changes or circulatory instability
- Electrolyte disturbances, including high potassium or low phosphate
- Metabolic alkalosis or high blood glucose
- Markedly high or low blood pressure
- Severe muscle cramps or spasms
- Nausea or vomiting associated with significant fluid or electrolyte disturbance
calcium chloride dihydrate + glucose monohydrate + magnesium chloride hexahydrate + potassium chloride + sodium chloride + sodium hydrogen carbonate in pregnancy
Human pregnancy data are unavailable. Use may be considered when necessary, with specialist renal and obstetric oversight.
calcium chloride dihydrate + glucose monohydrate + magnesium chloride hexahydrate + potassium chloride + sodium chloride + sodium hydrogen carbonate while breastfeeding
Use may be considered when necessary. The renal or critical-care team should assess the mother’s condition and concurrent medicines.
calcium chloride dihydrate + glucose monohydrate + magnesium chloride hexahydrate + potassium chloride + sodium chloride + sodium hydrogen carbonate interactions
Haemofiltration can alter medicine concentrations and fluid or electrolyte balance.
Filterable medicines, particularly those with low protein binding
Blood concentrations may fall as they pass through the filter.
Digoxin and other digitalis glycosides
Changes in potassium, magnesium or calcium can reveal or precipitate digitalis toxicity, including arrhythmias.
Vitamin D and calcium-containing products
Combined use can increase the risk of excessive blood calcium.
Common questions about calcium chloride dihydrate + glucose monohydrate + magnesium chloride hexahydrate + potassium chloride + sodium chloride + sodium hydrogen carbonate
Answers are fully visible for fast scanning and source review.
Is it taken by mouth?
No. Trained hospital staff deliver it into the extracorporeal blood circuit during haemofiltration.
Why does it have two chambers?
The bicarbonate and electrolyte components are stored separately for stability and must be thoroughly mixed before use.
Sources
These sources were used to prepare and review this medicine page.
Prepared and reviewed by the iatroX editorial team.