aspirin + caffeine citrate + paracetamol at a glance
Medicine class
Combination analgesic containing an NSAID, paracetamol and caffeine.
Main role
Relieves mild-to-moderate pain and feverish symptoms, including headache and migraine.
Age restriction
Not for children under 16 unless specifically directed by a doctor; for migraine, the selected product is not recommended below 18.
Administration
The soluble tablets must be dissolved in water before drinking.
Important check
Do not combine with another paracetamol-containing product or another NSAID, including aspirin.
What is aspirin + caffeine citrate + paracetamol used for?
The selected product is licensed for mild-to-moderate pain and feverish symptoms.
Headache and migraine
Neuralgia and toothache
Sore throat and period pain
Sprains, strains, muscular aches and pains
Rheumatic pain, sciatica, lumbago and fibrositis
Joint swelling and stiffness
Influenza, feverishness and feverish colds
How does aspirin + caffeine citrate + paracetamol work?
Aspirin reduces prostaglandin and thromboxane formation, helping reduce pain, inflammation and fever while also affecting platelets. Paracetamol acts mainly in the central nervous system to reduce pain and fever. Caffeine is a stimulant and analgesic adjunct that may support headache relief and the painkillers’ effects.
How to take aspirin + caffeine citrate + paracetamol
Follow the product label and leaflet. Fully dissolve the selected soluble tablets in water before drinking.
Check other pain, cold and flu products for paracetamol, aspirin or another NSAID before using them together.
Avoid excessive caffeine from coffee, tea, energy drinks and other sources.
aspirin + caffeine citrate + paracetamol side effects
Common or expected effects
- Indigestion or stomach ache
- Bleeding or bruising more easily than usual
Get urgent medical advice
- Stomach ulcer or gastrointestinal bleeding, including vomiting blood or black tar-like stools
- Severe allergic reaction, facial or throat swelling, wheezing or breathing difficulty
- Severe blistering, peeling or widespread skin reaction
- Unexpected jaundice, marked nausea or other symptoms suggesting liver dysfunction
- Unusual or prolonged bleeding
- Severe restlessness, palpitations or other marked stimulant effects
aspirin + caffeine citrate + paracetamol in pregnancy
This combination is not recommended during pregnancy and is contraindicated in the third trimester. Aspirin used for pain is generally not advised unless prescribed, particularly from 20 weeks. Paracetamol alone is generally preferred; ask a pharmacist, midwife or doctor about an alternative.
aspirin + caffeine citrate + paracetamol while breastfeeding
The selected combination should not be used while breastfeeding. Aspirin taken for pain is not recommended because of possible infant bleeding and theoretical Reye's syndrome risk, while caffeine may cause infant irritability or poor sleep. Paracetamol alone is usually preferred; ask a pharmacist, midwife or doctor about an alternative.
aspirin + caffeine citrate + paracetamol interactions
Check with a pharmacist or prescriber before combining this product with other medicines, especially those affecting bleeding, the kidneys or the liver.
Other NSAIDs, including aspirin and COX-2 inhibitors
Combining them increases adverse-effect risks, particularly gastrointestinal and kidney problems.
Anticoagulants and antiplatelet medicines
Aspirin can enhance their effects and increase bleeding risk.
Corticosteroids or SSRIs
Concurrent use can further increase gastrointestinal bleeding risk.
Common questions about aspirin + caffeine citrate + paracetamol
Answers are fully visible for fast scanning and source review.
Can it be taken with other paracetamol products?
No. Combining it with another paracetamol-containing painkiller, cold remedy or flu product can cause an overdose and serious delayed liver damage.
Can it be taken with ibuprofen?
The selected product should not be combined with ibuprofen or another systemic NSAID because adverse effects can be additive.
Can it be used for migraine?
Sources
These sources were used to prepare and review this medicine page.
Prepared and reviewed by the iatroX editorial team.