Answer
Golimumab is a human monoclonal antibody that forms high-affinity, stable complexes with both soluble and transmembrane bioactive forms of human TNF-α, preventing TNF-α from binding to its receptors.
Sources for this answer
- Simponi 50 mg solution for injection in pre filled syringeJanssen-Cilag Ltd (a Johnson & Johnson Company) · emc · SmPC §5.1 Pharmacodynamic properties · Version 41Document updated
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