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Medicines ivacaftor + lumacaftorQuestion & answer

ivacaftor + lumacaftor · Medicine question

Can Orkambi increase blood pressure?

iatroX medicinesPublished 8 November 2026

The answer

Answer

Orkambi can increase blood pressure in some patients, and blood pressure should be monitored periodically in all patients during treatment.

Sources for this answer

Orkambi 200 mg/125 mg film coated tabletsVertex Pharmaceuticals (Europe) Limited · emc · SmPC §4.4 Special warnings and precautions for use · Version 19Document updated 12 December 2025

Sources checked 8 November 2026

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ivacaftor + lumacaftor

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