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Medicines ivacaftor + lumacaftorQuestion & answer

ivacaftor + lumacaftor · Medicine question

Can Orkambi tablets be chewed, broken or dissolved?

iatroX medicinesPublished 8 November 2026

The answer

Answer

Orkambi tablets must be swallowed whole and should not be chewed, broken or dissolved.

Sources for this answer

Orkambi 200 mg/125 mg film coated tabletsVertex Pharmaceuticals (Europe) Limited · emc · SmPC §4.2 Posology and method of administration · Version 19Document updated 12 December 2025

Sources checked 8 November 2026

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ivacaftor + lumacaftor

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