Answer
Grapefruit-containing food and drink should be avoided during ivacaftor treatment because grapefruit juice contains components that moderately inhibit CYP3A and may increase ivacaftor exposure.
Sources for this answer
- Kalydeco 150 mg film-coated tabletsVertex Pharmaceuticals (Europe) Limited · emc · SmPC §4.5 Interaction with other medicinal products · Version 35Document updated
Sources checked