Answer
Kalydeco (ivacaftor) film-coated tablets should be swallowed whole, not chewed, crushed or broken, because no clinical data currently support other methods of administration.
Sources for this answer
- Kalydeco 150 mg film-coated tabletsVertex Pharmaceuticals (Europe) Limited · emc · SmPC §4.2 Posology and method of administration · Version 35Document updated
Sources checked