Answer
Zestoretic (hydrochlorothiazide + lisinopril) is contraindicated with sacubitril/valsartan because concurrent use increases the risk of angioedema, and at least 36 hours must separate stopping either treatment and starting the other.
Sources for this answer
- Zestoretic 20Atnahs Pharma UK Ltd · emc · SmPC §4.4 Special warnings and precautions for use · Version 23Document updated
Sources checked