talazoparib tosylate · Medicine question

Why is Talzenna not recommended during pregnancy?

iatroX medicinesPublished 8 November 2026

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Talzenna is not recommended during pregnancy because it may cause foetal harm, animal studies have shown embryo-foetal toxicity, and there are no data on its use in pregnant women.

Sources for this answer

Talzenna 1mg Hard CapsulesPfizer Limited · emc · SmPC §4.6 Fertility, pregnancy and lactation · Version 10Document updated 14 July 2025

Sources checked 8 November 2026

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For how long must women of childbearing potential use highly effective contraception during and after Talzenna treatment?For how long is breastfeeding contraindicated during and after Talzenna treatment?How can Talzenna affect the ability to drive or use machines?How does itraconazole affect exposure to Talzenna?What are the most common adverse effects reported with Talzenna in clinical studies?Which adults with breast cancer is Talzenna indicated to treat?

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