Answer
Spironolactone is not recommended with abiraterone acetate (Zytiga) because it binds to the androgen receptor and may increase prostate-specific antigen (PSA) levels.
Sources for this answer
- ZYTIGA 500 mg film-coated tabletsJanssen-Cilag Ltd (a Johnson & Johnson Company) · emc · SmPC §4.5 Interaction with other medicinal products · Version 12Document updated
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