Answer
Abiraterone acetate is converted in the body to abiraterone, which selectively inhibits CYP17, an enzyme required to produce androgens in testicular, adrenal and prostatic tumour tissues, thereby reducing formation of testosterone precursors.
Sources for this answer
- ZYTIGA 500 mg film-coated tabletsJanssen-Cilag Ltd (a Johnson & Johnson Company) · emc · SmPC §5.1 Pharmacodynamic properties · Version 12Document updated
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