Answer
In healthy subjects, pretreatment with rifampicin 600 mg daily for six days followed by a single 1,000 mg dose of abiraterone acetate decreased mean plasma abiraterone exposure (AUC) by 55%.
Sources for this answer
- ZYTIGA 500 mg film-coated tabletsJanssen-Cilag Ltd (a Johnson & Johnson Company) · emc · SmPC §4.5 Interaction with other medicinal products · Version 12Document updated
Sources checked