Answer
Midostaurin (Rydapt) is not recommended during pregnancy because it can harm the foetus, animal studies demonstrated foetotoxicity, and there are no adequate, well-controlled studies in pregnant women.
Sources for this answer
- Rydapt 25 mg soft capsulesNovartis Pharmaceuticals UK Ltd · emc · SmPC §4.6 Fertility, pregnancy and lactation · Version 10Document updated
Sources checked