Answer
Eplerenone is contraindicated with clarithromycin because clarithromycin strongly inhibits CYP3A4, which can cause significant pharmacokinetic interactions and increased eplerenone exposure.
Sources for this answer
- Inspra 25 mg Film-coated TabletsViatris (formerly Mylan or Upjohn) · emc · SmPC §4.5 Interaction with other medicinal products · Version 17Document updated
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