Answer
Taking trimethoprim with eplerenone increases the risk of hyperkalaemia (high blood potassium), so serum potassium and kidney function should be monitored, particularly in older people and those with renal impairment.
Sources for this answer
- Inspra 25 mg Film-coated TabletsViatris (formerly Mylan or Upjohn) · emc · SmPC §4.5 Interaction with other medicinal products · Version 17Document updated
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