Answer
Cobicistat slows CYP3A-mediated breakdown of elvitegravir, maintaining its exposure. It does not directly inhibit HIV.
Sources for this answer
- Elvitegravir/Cobicistat/Emtricitabine/Tenofovir Disoproxil Gilead150 mg/150 mg/200 mg/245 mg film-coated tablets — Current selected SmPCemc · Summary of Product Characteristics
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