Answer
Pemigatinib may increase blood creatinine by decreasing renal tubular creatinine secretion through possible inhibition of renal transporters OCT2 and MATE1, which may not affect glomerular function.
Sources for this answer
- Pemazyre 4.5 mg - tabletsIncyte Biosciences UK Ltd · emc · SmPC §4.4 Special warnings and precautions for use · Version 5Document updated
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