Answer
Itraconazole 200 mg once daily, a strong CYP3A4 inhibitor, increased pemigatinib geometric mean AUC by 88% (90% CI: 75%–103%), potentially increasing the incidence and severity of pemigatinib adverse reactions.
Sources for this answer
- Pemazyre 4.5 mg - tabletsIncyte Biosciences UK Ltd · emc · SmPC §4.5 Interaction with other medicinal products · Version 5Document updated
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