Answer
Baseline and follow-up eye examinations are recommended for children starting Kaftrio with ivacaftor because non-congenital lens opacities without impact on vision have been reported with ivacaftor-containing regimens, and a treatment-related risk cannot be excluded.
Sources for this answer
- Kaftrio 75 mg/50 mg/100 mg film-coated tabletsVertex Pharmaceuticals (Europe) Limited · emc · SmPC §4.4 Special warnings and precautions for use · Version 16Document updated
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