Answer
Strong CYP3A4 inducers including rifampicin, phenobarbital, carbamazepine, phenytoin and St John's wort extract should be avoided with voxelotor because they may decrease voxelotor exposure and reduce efficacy.
Sources for this answer
- Oxbryta 500 mg film-coated tabletsPfizer Limited · emc · SmPC §4.5 Interaction with other medicinal products · Version 5Document updated
Sources checked