Answer
Voxelotor binds to haemoglobin S and increases haemoglobin’s oxygen affinity, producing dose-dependent inhibition of haemoglobin S polymerisation and thereby inhibiting red blood cell sickling and improving cell deformability.
Sources for this answer
- Oxbryta 500 mg film-coated tabletsPfizer Limited · emc · SmPC §5.1 Pharmacodynamic properties · Version 5Document updated
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